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    • Acid ceramidase promotes nuclear export of PTEN through sphingosine 1-phosphate mediated Akt signaling.
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Acid ceramidase promotes nuclear export of PTEN through sphingosine 1-phosphate mediated Akt signaling.

Acid ceramidase promotes nuclear export of PTEN through sphingosine 1-phosphate mediated Akt signaling. PLoS One. 2013; 8(10):e76593.

View in: PubMed

subject areas
  • Acid Ceramidase
  • Active Transport, Cell Nucleus
  • Adenocarcinoma
  • Animals
  • Antineoplastic Agents
  • Apoptosis
  • Cell Cycle
  • Cell Line, Tumor
  • Cell Nucleus
  • Cytoplasm
  • Drug Resistance, Neoplasm
  • Gene Expression Regulation, Neoplastic
  • Humans
  • Karyopherins
  • Lysophospholipids
  • Male
  • Mice
  • Neoplasm Transplantation
  • Phosphatidylinositol 3-Kinases
  • Prostatic Neoplasms
  • Proto-Oncogene Proteins c-akt
  • PTEN Phosphohydrolase
  • Receptors, Cytoplasmic and Nuclear
  • Signal Transduction
  • Sphingosine
  • Taxoids

authors with profiles
  • Joseph C. Cheng
  • James S. Norris
  • Xiang Liu