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One or more keywords matched the following properties of Yoon, Je-hyun
overview My main research interest is to understand the “RNP Code”, that is, the composition and function of RNA-binding proteins bound to RNAs, both coding and noncoding. I have contributed to efforts to characterize the assembly, composition, and function of ribonucleoprotein (RNP) particles, the influence of long noncoding (lnc)RNAs in translation and ubiquitin-mediated proteolysis, and the mechanisms that determine lncRNA abundance in the cell. I am interested in elucidating the rules that govern the assembly of RBPs into RNA-containing functional complexes, the influence of signaling events that regulate RNPs, and the impact of specific RBPs and RNAs on RNP activity and ensuing gene regulation. I am particularly interested in studying the consequences of RNPs on cellular events such as proliferation, survival, senescence, aging, and age-associated human diseases such as cancer. In my laboratory, I will strive to understand the role of RNPs in human physiology and in disease processes.
One or more keywords matched the following items that are connected to Yoon, Je-hyun
Item TypeName
Concept RNA
Concept RNA Interference
Concept RNA Cap-Binding Proteins
Concept RNA, Fungal
Concept RNA, Untranslated
Concept RNA Stability
Concept RNA, Messenger
Concept Sequence Analysis, RNA
Concept RNA Processing, Post-Transcriptional
Concept DEAD-box RNA Helicases
Concept RNA Splicing
Concept RNA-Binding Proteins
Award or Honor Receipt RNA Society Scaringe Awards
Academic Article AUF1 promotes let-7b loading on Argonaute 2.
Academic Article Long noncoding RNA turnover.
Academic Article PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity.
Academic Article Ribonucleoprotein therapy in Alzheimer's disease?
Academic Article Functional interactions among microRNAs and long noncoding RNAs.
Academic Article Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination.
Academic Article Tyrosine phosphorylation of HuR by JAK3 triggers dissociation and degradation of HuR target mRNAs.
Academic Article Posttranscriptional gene regulation by long noncoding RNA.
Academic Article LincRNA-p21 suppresses target mRNA translation.
Academic Article MS2-TRAP (MS2-tagged RNA affinity purification): tagging RNA to identify associated miRNAs.
Academic Article Dcp2 phosphorylation by Ste20 modulates stress granule assembly and mRNA decay in Saccharomyces cerevisiae.
Academic Article Cross-Linking Immunoprecipitation and qPCR (CLIP-qPCR) Analysis to Map Interactions Between Long Noncoding RNAs and RNA-Binding Proteins.
Academic Article Identification of mRNA-Interacting Factors by MS2-TRAP (MS2-Tagged RNA Affinity Purification).
Concept RNA, Long Noncoding
Search Criteria
  • RNA