"RNA Stability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The extent to which an RNA molecule retains its structural integrity and resists degradation by RNASE, and base-catalyzed HYDROLYSIS, under changing in vivo or in vitro conditions.
| Descriptor ID |
D020871
|
| MeSH Number(s) |
G02.111.780
|
| Concept/Terms |
mRNA Degradation- mRNA Degradation
- Degradation, mRNA
- mRNA Transcript Degradation
- Degradation, mRNA Transcript
- Transcript Degradation, mRNA
|
Below are MeSH descriptors whose meaning is more general than "RNA Stability".
Below are MeSH descriptors whose meaning is more specific than "RNA Stability".
This graph shows the total number of publications written about "RNA Stability" by people in this website by year, and whether "RNA Stability" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 2 | 3 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 5 | 5 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 3 | 3 |
| 2010 | 2 | 4 | 6 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 2 | 1 | 3 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 2 | 3 |
| 2021 | 1 | 2 | 3 |
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Below are the most recent publications written about "RNA Stability" by people in Profiles.
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RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site. Cell Rep. 2021 11 02; 37(5):109934.
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Biomolecular condensates amplify mRNA decapping by biasing enzyme conformation. Nat Chem Biol. 2021 05; 17(5):615-623.
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EDC3 phosphorylation regulates growth and invasion through controlling P-body formation and dynamics. EMBO Rep. 2021 04 07; 22(4):e50835.
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Bone marrow deficiency of mRNA decaying protein Tristetraprolin increases inflammation and mitochondrial ROS but reduces hepatic lipoprotein production in LDLR knockout mice. Redox Biol. 2020 10; 37:101609.
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Pdc2/Pat1 increases the range of decay factors and RNA bound by the Lsm1-7 complex. RNA. 2020 10; 26(10):1380-1388.
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RNA binding protein FXR1-miR301a-3p axis contributes to p21WAF1 degradation in oral cancer. PLoS Genet. 2020 01; 16(1):e1008580.
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Pat1 activates late steps in mRNA decay by multiple mechanisms. Proc Natl Acad Sci U S A. 2019 11 19; 116(47):23512-23517.
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Structural and molecular mechanisms for the control of eukaryotic 5'-3' mRNA decay. Nat Struct Mol Biol. 2018 12; 25(12):1077-1085.
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Control of mRNA decapping by autoinhibition. Nucleic Acids Res. 2018 07 06; 46(12):6318-6329.
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Structural basis of mRNA-cap recognition by Dcp1-Dcp2. Nat Struct Mol Biol. 2016 Nov; 23(11):987-994.