"DEAD-box RNA Helicases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large family of RNA helicases that share a common protein motif with the single letter amino acid sequence D-E-A-D (Asp-Glu-Ala-Asp). In addition to RNA helicase activity, members of the DEAD-box family participate in other aspects of RNA metabolism and regulation of RNA function.
| Descriptor ID |
D053487
|
| MeSH Number(s) |
D08.811.913.696.445.735.720.249
|
| Concept/Terms |
DEAD-box RNA Helicases- DEAD-box RNA Helicases
- DEAD box RNA Helicases
- Helicases, DEAD-box RNA
- RNA Helicases, DEAD-box
DEAD Box Helicase p68- DEAD Box Helicase p68
- p68 RNA Helicase
- Helicase, p68 RNA
- RNA Helicase, p68
- p68 DEAD Box Protein
|
Below are MeSH descriptors whose meaning is more general than "DEAD-box RNA Helicases".
Below are MeSH descriptors whose meaning is more specific than "DEAD-box RNA Helicases".
This graph shows the total number of publications written about "DEAD-box RNA Helicases" by people in this website by year, and whether "DEAD-box RNA Helicases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 2 | 3 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 2 | 3 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "DEAD-box RNA Helicases" by people in Profiles.
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Polymorphism rs3742330 in microRNA Biogenesis Gene DICER1 Is Associated with Pseudoexfoliation Glaucoma in Saudi Cohort. Genes (Basel). 2022 03 10; 13(3).
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Pharmacological inhibition of DEAD-Box RNA Helicase 3 attenuates stress granule assembly. Biochem Pharmacol. 2020 12; 182:114280.
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DICER1-associated metastatic abdominopelvic primitive neuroectodermal tumor with an EWSR1 rearrangement in a 16-yr-old female. Cold Spring Harb Mol Case Stud. 2020 10; 6(5).
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Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development. Nat Commun. 2020 09 23; 11(1):4737.
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Inhibition of the Dead Box RNA Helicase 3 Prevents HIV-1 Tat and Cocaine-Induced Neurotoxicity by Targeting Microglia Activation. J Neuroimmune Pharmacol. 2020 06; 15(2):209-223.
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Identification of novel cancer therapeutic targets using a designed and pooled shRNA library screen. Sci Rep. 2017 02 22; 7:43023.
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Identification and characterization of Dicer1e, a Dicer1 protein variant, in oral cancer cells. Mol Cancer. 2014 Aug 13; 13:190.
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Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis. Am J Hum Genet. 2014 Jan 02; 94(1):47-61.
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Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production. PLoS Genet. 2013; 9(2):e1003222.
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Interaction between p68 RNA helicase and Ca2+-calmodulin promotes cell migration and metastasis. Nat Commun. 2013; 4:1354.