Amandine Rovini

Title
InstitutionMedical University of South Carolina
DepartmentDrug Discovery & Biomedical Science
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Rajendran M, Queralt-Martín M, Gurnev PA, Rosencrans WM, Rovini A, Jacobs D, Abrantes K, Hoogerheide DP, Bezrukov SM, Rostovtseva TK. Restricting a-synuclein transport into mitochondria by inhibition of a-synuclein-VDAC complexation as a potential therapeutic target for Parkinson's disease treatment. Cell Mol Life Sci. 2022 Jun 19; 79(7):368. PMID: 35718804.
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    2. Msheik Z, El Massry M, Rovini A, Billet F, Desmoulière A. The macrophage: a key player in the pathophysiology of peripheral neuropathies. J Neuroinflammation. 2022 Apr 16; 19(1):97. PMID: 35429971.
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    3. Heslop KA, Rovini A, Gooz M, Maldonado EN. Fast Determination of Mitochondrial Metabolism and Respiratory Complex Activity in Permeabilized and Intact Cells. Methods Mol Biol. 2022; 2497:1-10. PMID: 35771432.
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    4. Bernard A, Danigo A, Bourthoumieu S, Mroué M, Desmoulière A, Sturtz F, Rovini A, Demiot C. The Cholecystokinin Type 2 Receptor, a Pharmacological Target for Pain Management. Pharmaceuticals (Basel). 2021 Nov 19; 14(11). PMID: 34832967.
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    5. Danigo A, Rovini A, Bessaguet F, Bouchenaki H, Bernard A, Sturtz F, Bourthoumieu S, Desmoulière A, Magy L, Demiot C. The Angiotensin II Type 2 Receptor, a Target for Protection and Regeneration of the Peripheral Nervous System? Pharmaceuticals (Basel). 2021 Feb 24; 14(3). PMID: 33668331.
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    6. Meyenberg Cunha-de Padua M, Fabbri L, Dufies M, Lacas-Gervais S, Contenti J, Voyton C, Fazio S, Irondelle M, Mograbi B, Rouleau M, Sadaghianloo N, Rovini A, Brenner C, Craigen WJ, Bourgeais J, Herault O, Bost F, Mazure NM. Evidences of a Direct Relationship between Cellular Fuel Supply and Ciliogenesis Regulated by Hypoxic VDAC1-?C. Cancers (Basel). 2020 Nov 23; 12(11). PMID: 33238609.
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    7. Rovini A, Heslop K, Hunt EG, Morris ME, Fang D, Gooz M, Gerencser AA, Maldonado EN. Quantitative analysis of mitochondrial membrane potential heterogeneity in unsynchronized and synchronized cancer cells. FASEB J. 2021 01; 35(1):e21148. PMID: 33196122.
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    8. Rovini A, Gurnev PA, Beilina A, Queralt-Martín M, Rosencrans W, Cookson MR, Bezrukov SM, Rostovtseva TK. Correction to: Molecular mechanism of olesoxime-mediated neuroprotection through targeting a-synuclein interaction with mitochondrial VDAC. Cell Mol Life Sci. 2020 09; 77(18):3691-3692. PMID: 31919572.
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    9. Rovini A, Gurnev PA, Beilina A, Queralt-Martín M, Rosencrans W, Cookson MR, Bezrukov SM, Rostovtseva TK. Molecular mechanism of olesoxime-mediated neuroprotection through targeting a-synuclein interaction with mitochondrial VDAC. Cell Mol Life Sci. 2020 Sep; 77(18):3611-3626. PMID: 31760463.
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    10. Heslop KA, Rovini A, Hunt EG, Fang D, Morris ME, Christie CF, Gooz MB, DeHart DN, Dang Y, Lemasters JJ, Maldonado EN. JNK activation and translocation to mitochondria mediates mitochondrial dysfunction and cell death induced by VDAC opening and sorafenib in hepatocarcinoma cells. Biochem Pharmacol. 2020 01; 171:113728. PMID: 31759978.
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    11. Ankam S, Rovini A, Baheti S, Hrstka R, Wu Y, Schmidt K, Wang H, Madigan N, Koenig LS, Stelzig K, Resch Z, Klein CJ, Sun Z, Staff NP. DNA methylation patterns in human iPSC-derived sensory neuronal differentiation. Epigenetics. 2019 09; 14(9):927-937. PMID: 31148524.
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    12. Rovini A. Tubulin-VDAC Interaction: Molecular Basis for Mitochondrial Dysfunction in Chemotherapy-Induced Peripheral Neuropathy. Front Physiol. 2019; 10:671. PMID: 31214047.
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    13. Christie CF, Fang D, Hunt EG, Morris ME, Rovini A, Heslop KA, Beeson GC, Beeson CC, Maldonado EN. Statin-dependent modulation of mitochondrial metabolism in cancer cells is independent of cholesterol content. FASEB J. 2019 07; 33(7):8186-8201. PMID: 30951369.
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    14. Jacobs D, Hoogerheide DP, Rovini A, Jiang Z, Lee JC, Rostovtseva TK, Bezrukov SM. Probing Membrane Association of a-Synuclein Domains with VDAC Nanopore Reveals Unexpected Binding Pattern. Sci Rep. 2019 03 14; 9(1):4580. PMID: 30872688.
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    15. Rostovtseva TK, Gurnev PA, Hoogerheide DP, Rovini A, Sirajuddin M, Bezrukov SM. Sequence diversity of tubulin isotypes in regulation of the mitochondrial voltage-dependent anion channel. J Biol Chem. 2018 07 13; 293(28):10949-10962. PMID: 29777059.
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    16. Le Grand M, Rovini A, Bourgarel-Rey V, Honore S, Bastonero S, Braguer D, Carre M. ROS-mediated EB1 phosphorylation through Akt/GSK3ß pathway: implication in cancer cell response to microtubule-targeting agents. Oncotarget. 2014 May 30; 5(10):3408-23. PMID: 24930764.
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    17. Rovini A, Gauthier G, Bergès R, Kruczynski A, Braguer D, Honoré S. Anti-migratory effect of vinflunine in endothelial and glioblastoma cells is associated with changes in EB1 C-terminal detyrosinated/tyrosinated status. PLoS One. 2013; 8(6):e65694. PMID: 23750272.
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    18. Savry A, Carre M, Berges R, Rovini A, Pobel I, Chacon C, Braguer D, Bourgarel-Rey V. Bcl-2-enhanced efficacy of microtubule-targeting chemotherapy through Bim overexpression: implications for cancer treatment. Neoplasia. 2013 Jan; 15(1):49-60. PMID: 23358890.
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    19. Rovini A, Savry A, Braguer D, Carré M. Microtubule-targeted agents: when mitochondria become essential to chemotherapy. Biochim Biophys Acta. 2011 Jun; 1807(6):679-88. PMID: 21216222.
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    20. Rovini A, Carré M, Bordet T, Pruss RM, Braguer D. Olesoxime prevents microtubule-targeting drug neurotoxicity: selective preservation of EB comets in differentiated neuronal cells. Biochem Pharmacol. 2010 Sep 15; 80(6):884-94. PMID: 20417191.
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