Receptor, Macrophage Colony-Stimulating Factor

"Receptor, Macrophage Colony-Stimulating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A receptor for MACROPHAGE COLONY-STIMULATING FACTOR encoded by the c-fms proto-oncogene (GENES, FMS). It contains an intrinsic protein-tyrosine kinase activity. When activated the receptor undergoes autophosphorylation, phosphorylation of down-stream signaling molecules and rapid down-regulation.

Descriptor ID	D016186
MeSH Number(s)	D08.811.913.696.620.682.725.400.500 D12.776.543.750.630.492 D12.776.543.750.705.852.150.150 D12.776.543.750.750.400.200.200 D12.776.624.664.700.800
Concept/Terms	Receptor, Macrophage Colony-Stimulating Factor Receptor, Macrophage Colony-Stimulating Factor Receptor, Macrophage Colony Stimulating Factor Macrophage Colony-Stimulating Factor Receptors Macrophage Colony Stimulating Factor Receptors c-fms Protein c fms Protein Receptor, CSF-1 Receptor, CSF 1 Receptors, CSF-1 CSF-1 Receptors Receptors, CSF 1 CD115 Antigens Proto-Oncogene Protein fms M-CSF Receptors Receptors, M-CSF Receptors, M CSF Receptors, Macrophage Colony-Stimulating Factor Receptors, Macrophage Colony Stimulating Factor CD115 Antigen Antigen, CD115 Antigens, CD115 CSF-1 Receptor fms Proto-Oncogene Protein Proto-Oncogene Protein, fms fms Proto Oncogene Protein

Below are MeSH descriptors whose meaning is more general than "Receptor, Macrophage Colony-Stimulating Factor".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
Receptor, Macrophage Colony-Stimulating Factor [D08.811.913.696.620.682.725.400.500]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptor Protein-Tyrosine Kinases [D12.776.543.750.630]
Receptor, Macrophage Colony-Stimulating Factor [D12.776.543.750.630.492]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Cytokine [D12.776.543.750.705.852]
Receptors, Colony-Stimulating Factor [D12.776.543.750.705.852.150]
Receptor, Macrophage Colony-Stimulating Factor [D12.776.543.750.705.852.150.150]
Receptors, Peptide [D12.776.543.750.750]
Receptors, Growth Factor [D12.776.543.750.750.400]
Receptors, Colony-Stimulating Factor [D12.776.543.750.750.400.200]
Receptor, Macrophage Colony-Stimulating Factor [D12.776.543.750.750.400.200.200]
Neoplasm Proteins [D12.776.624]
Oncogene Proteins [D12.776.624.664]
Proto-Oncogene Proteins [D12.776.624.664.700]
Receptor, Macrophage Colony-Stimulating Factor [D12.776.624.664.700.800]

Below are MeSH descriptors whose meaning is related to "Receptor, Macrophage Colony-Stimulating Factor".

Below are MeSH descriptors whose meaning is more specific than "Receptor, Macrophage Colony-Stimulating Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptor, Macrophage Colony-Stimulating Factor" by people in this website by year, and whether "Receptor, Macrophage Colony-Stimulating Factor" was a major or minor topic of these publications.

Bar chart showing 10 publications over 9 distinct years, with a maximum of 2 publications in 1998

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	0	1
1997	1	0	1
1998	1	1	2
1999	0	1	1
2000	0	1	1
2001	1	0	1
2002	1	0	1
2008	1	0	1
2012	0	1	1

Below are the most recent publications written about "Receptor, Macrophage Colony-Stimulating Factor" by people in Profiles.

Schiopu A, Nadig SN, Cotoi OS, Hester J, van Rooijen N, Wood KJ. Inflammatory Ly-6C(hi) monocytes play an important role in the development of severe transplant arteriosclerosis in hyperlipidemic recipients. Atherosclerosis. 2012 Aug; 223(2):291-8.

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Hume DA, Sasmono T, Himes SR, Sharma SM, Bronisz A, Constantin M, Ostrowski MC, Ross IL. The Ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene. J Immunol. 2008 May 15; 180(10):6733-42.

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Sasmono RT, Oceandy D, Pollard JW, Tong W, Pavli P, Wainwright BJ, Ostrowski MC, Himes SR, Hume DA. A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. Blood. 2003 Feb 01; 101(3):1155-63.

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Wang Y, Zheng GG, Wu KF, Li G, Rao Q. Construction of macrophage colony-stimulating factor receptor DNA vaccine. Haematologica. 2001 Nov; 86(11):1219-20.

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Luchin A, Purdom G, Murphy K, Clark MY, Angel N, Cassady AI, Hume DA, Ostrowski MC. The microphthalmia transcription factor regulates expression of the tartrate-resistant acid phosphatase gene during terminal differentiation of osteoclasts. J Bone Miner Res. 2000 Mar; 15(3):451-60.

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Lichanska AM, Browne CM, Henkel GW, Murphy KM, Ostrowski MC, McKercher SR, Maki RA, Hume DA. Differentiation of the mononuclear phagocyte system during mouse embryogenesis: the role of transcription factor PU.1. Blood. 1999 Jul 01; 94(1):127-38.

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Fowles LF, Martin ML, Nelsen L, Stacey KJ, Redd D, Clark YM, Nagamine Y, McMahon M, Hume DA, Ostrowski MC. Persistent activation of mitogen-activated protein kinases p42 and p44 and ets-2 phosphorylation in response to colony-stimulating factor 1/c-fms signaling. Mol Cell Biol. 1998 Sep; 18(9):5148-56.

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Ross IL, Yue X, Ostrowski MC, Hume DA. Interaction between PU.1 and another Ets family transcription factor promotes macrophage-specific Basal transcription initiation. J Biol Chem. 1998 Mar 20; 273(12):6662-9.

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Hume DA, Yue X, Ross IL, Favot P, Lichanska A, Ostrowski MC. Regulation of CSF-1 receptor expression. Mol Reprod Dev. 1997 Jan; 46(1):46-52; discussion 52-3.

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Reddy MA, Yang BS, Yue X, Barnett CJ, Ross IL, Sweet MJ, Hume DA, Ostrowski MC. Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes. J Exp Med. 1994 Dec 01; 180(6):2309-19.

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