Receptor, Macrophage Colony-Stimulating Factor
"Receptor, Macrophage Colony-Stimulating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A receptor for MACROPHAGE COLONY-STIMULATING FACTOR encoded by the c-fms proto-oncogene (GENES, FMS). It contains an intrinsic protein-tyrosine kinase activity. When activated the receptor undergoes autophosphorylation, phosphorylation of down-stream signaling molecules and rapid down-regulation.
| Descriptor ID |
D016186
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.500 D12.776.543.750.630.492 D12.776.543.750.705.852.150.150 D12.776.543.750.750.400.200.200 D12.776.624.664.700.800
|
| Concept/Terms |
Receptor, Macrophage Colony-Stimulating Factor- Receptor, Macrophage Colony-Stimulating Factor
- Receptor, Macrophage Colony Stimulating Factor
- Macrophage Colony-Stimulating Factor Receptors
- Macrophage Colony Stimulating Factor Receptors
- c-fms Protein
- c fms Protein
- Receptor, CSF-1
- Receptor, CSF 1
- Receptors, CSF-1
- CSF-1 Receptors
- Receptors, CSF 1
- CD115 Antigens
- Proto-Oncogene Protein fms
- M-CSF Receptors
- Receptors, M-CSF
- Receptors, M CSF
- Receptors, Macrophage Colony-Stimulating Factor
- Receptors, Macrophage Colony Stimulating Factor
- CD115 Antigen
- Antigen, CD115
- Antigens, CD115
- CSF-1 Receptor
- fms Proto-Oncogene Protein
- Proto-Oncogene Protein, fms
- fms Proto Oncogene Protein
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Macrophage Colony-Stimulating Factor".
- Chemicals and Drugs [D]
- Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
- Transferases [D08.811.913]
- Phosphotransferases [D08.811.913.696]
- Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
- Protein Kinases [D08.811.913.696.620.682]
- Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
- Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
- Receptor, Macrophage Colony-Stimulating Factor [D08.811.913.696.620.682.725.400.500]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptor Protein-Tyrosine Kinases [D12.776.543.750.630]
- Receptor, Macrophage Colony-Stimulating Factor [D12.776.543.750.630.492]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Colony-Stimulating Factor [D12.776.543.750.705.852.150]
- Receptor, Macrophage Colony-Stimulating Factor [D12.776.543.750.705.852.150.150]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Growth Factor [D12.776.543.750.750.400]
- Receptors, Colony-Stimulating Factor [D12.776.543.750.750.400.200]
- Receptor, Macrophage Colony-Stimulating Factor [D12.776.543.750.750.400.200.200]
- Neoplasm Proteins [D12.776.624]
- Oncogene Proteins [D12.776.624.664]
- Proto-Oncogene Proteins [D12.776.624.664.700]
- Receptor, Macrophage Colony-Stimulating Factor [D12.776.624.664.700.800]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Macrophage Colony-Stimulating Factor".
This graph shows the total number of publications written about "Receptor, Macrophage Colony-Stimulating Factor" by people in this website by year, and whether "Receptor, Macrophage Colony-Stimulating Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor, Macrophage Colony-Stimulating Factor" by people in Profiles.
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Inflammatory Ly-6C(hi) monocytes play an important role in the development of severe transplant arteriosclerosis in hyperlipidemic recipients. Atherosclerosis. 2012 Aug; 223(2):291-8.
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The Ewing sarcoma protein (EWS) binds directly to the proximal elements of the macrophage-specific promoter of the CSF-1 receptor (csf1r) gene. J Immunol. 2008 May 15; 180(10):6733-42.
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Construction of macrophage colony-stimulating factor receptor DNA vaccine. Haematologica. 2001 Nov; 86(11):1219-20.
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The microphthalmia transcription factor regulates expression of the tartrate-resistant acid phosphatase gene during terminal differentiation of osteoclasts. J Bone Miner Res. 2000 Mar; 15(3):451-60.
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Differentiation of the mononuclear phagocyte system during mouse embryogenesis: the role of transcription factor PU.1. Blood. 1999 Jul 01; 94(1):127-38.
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Persistent activation of mitogen-activated protein kinases p42 and p44 and ets-2 phosphorylation in response to colony-stimulating factor 1/c-fms signaling. Mol Cell Biol. 1998 Sep; 18(9):5148-56.
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Interaction between PU.1 and another Ets family transcription factor promotes macrophage-specific Basal transcription initiation. J Biol Chem. 1998 Mar 20; 273(12):6662-9.
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Regulation of CSF-1 receptor expression. Mol Reprod Dev. 1997 Jan; 46(1):46-52; discussion 52-3.
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Opposing actions of c-ets/PU.1 and c-myb protooncogene products in regulating the macrophage-specific promoters of the human and mouse colony-stimulating factor-1 receptor (c-fms) genes. J Exp Med. 1994 Dec 01; 180(6):2309-19.
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An enhancer element responsive to ras and fms signaling pathways is composed of two distinct nuclear factor binding sites. Mol Endocrinol. 1992 Jul; 6(7):1051-60.