Receptor, trkB

"Receptor, trkB" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A protein-tyrosine kinase receptor that is specific for BRAIN-DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN 3; neurotrophin 4 and neurotrophin 5. It is widely expressed in nervous tissue and plays a role in mediating the effects of neurotrophins on growth and differentiation of neuronal cells.

Descriptor ID	D020813
MeSH Number(s)	D08.811.913.696.620.682.725.400.700 D12.776.543.750.630.498 D12.776.543.750.750.400.550.600
Concept/Terms	Receptor, trkB Receptor, trkB BDNF Receptor Receptor, BDNF trkB Receptor Receptor, Neurotrophic Tyrosine Kinase Type 2 NTRK2 Receptor Receptor, NTRK2 Brain Derived Neurotrophic Factor Receptor Neurotrophic Tyrosine Kinase Receptor Type 2 trkB(gp145) Protein Neurotrophic Factor, Brain-Derived, Receptor

Below are MeSH descriptors whose meaning is more general than "Receptor, trkB".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
Receptor, trkB [D08.811.913.696.620.682.725.400.700]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptor Protein-Tyrosine Kinases [D12.776.543.750.630]
Receptor, trkB [D12.776.543.750.630.498]
Receptors, Peptide [D12.776.543.750.750]
Receptors, Growth Factor [D12.776.543.750.750.400]
Receptors, Nerve Growth Factor [D12.776.543.750.750.400.550]
Receptor, trkB [D12.776.543.750.750.400.550.600]

Below are MeSH descriptors whose meaning is related to "Receptor, trkB".

Below are MeSH descriptors whose meaning is more specific than "Receptor, trkB".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptor, trkB" by people in this website by year, and whether "Receptor, trkB" was a major or minor topic of these publications.

Bar chart showing 19 publications over 13 distinct years, with a maximum of 3 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	2	0	2
2002	0	1	1
2003	1	0	1
2004	1	0	1
2008	0	1	1
2010	0	2	2
2011	1	1	2
2012	0	1	1
2014	1	0	1
2017	1	2	3
2018	0	1	1
2019	1	1	2
2020	0	1	1

Below are the most recent publications written about "Receptor, trkB" by people in Profiles.

Sims SK, Rizzo A, Howard K, Farrand A, Boger H, Adkins DL. Comparative Enhancement of Motor Function and BDNF Expression Following Different Brain Stimulation Approaches in an Animal Model of Ischemic Stroke. Neurorehabil Neural Repair. 2020 10; 34(10):925-935.

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Bharani KL, Ledreux A, Gilmore A, Carroll SL, Granholm AC. Serum pro-BDNF levels correlate with phospho-tau staining in Alzheimer's disease. Neurobiol Aging. 2020 03; 87:49-59.

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Farrand AQ, Helke KL, Aponte-Cofresí L, Gooz MB, Gregory RA, Hinson VK, Boger HA. Effects of vagus nerve stimulation are mediated in part by TrkB in a parkinson's disease model. Behav Brain Res. 2019 11 05; 373:112080.

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Bobadilla AC, Garcia-Keller C, Chareunsouk V, Hyde J, Medina Camacho D, Heinsbroek JA, Kalivas PW. Accumbens brain-derived neurotrophic factor (BDNF) transmission inhibits cocaine seeking. Addict Biol. 2019 09; 24(5):860-873.

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Anderson EM, Wissman AM, Chemplanikal J, Buzin N, Guzman D, Larson EB, Neve RL, Nestler EJ, Cowan CW, Self DW. BDNF-TrkB controls cocaine-induced dendritic spines in rodent nucleus accumbens dissociated from increases in addictive behaviors. Proc Natl Acad Sci U S A. 2017 08 29; 114(35):9469-9474.

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Alhusban A, Kozak A, Pillai B, Ahmed H, Sayed MA, Johnson MH, Ishrat T, Ergul A, Fagan SC. Mechanisms of acute neurovascular protection with AT1 blockade after stroke: Effect of prestroke hypertension. PLoS One. 2017; 12(6):e0178867.

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Wills MK, Keyvani Chahi A, Lau HR, Tilak M, Guild BD, New LA, Lu P, Jacquet K, Meakin SO, Bisson N, Jones N. Signaling adaptor ShcD suppresses extracellular signal-regulated kinase (Erk) phosphorylation distal to the Ret and Trk neurotrophic receptors. J Biol Chem. 2017 04 07; 292(14):5748-5759.

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Otis JM, Fitzgerald MK, Mueller D. Infralimbic BDNF/TrkB enhancement of GluN2B currents facilitates extinction of a cocaine-conditioned place preference. J Neurosci. 2014 Apr 23; 34(17):6057-64.

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Sakakima H, Khan M, Dhammu TS, Shunmugavel A, Yoshida Y, Singh I, Singh AK. Stimulation of functional recovery via the mechanisms of neurorepair by S-nitrosoglutathione and motor exercise in a rat model of transient cerebral ischemia and reperfusion. Restor Neurol Neurosci. 2012; 30(5):383-96.

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Khan M, Sakakima H, Dhammu TS, Shunmugavel A, Im YB, Gilg AG, Singh AK, Singh I. S-nitrosoglutathione reduces oxidative injury and promotes mechanisms of neurorepair following traumatic brain injury in rats. J Neuroinflammation. 2011 Jul 06; 8:78.

View in: PubMed

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