"Fluorodeoxyuridylate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
5-Fluoro-2'-deoxyuridylate. An inhibitor of thymidylate synthetase. Formed from 5-fluorouracil or 5-fluorodeoxyuridine.
| Descriptor ID |
D005468
|
| MeSH Number(s) |
D03.383.742.686.850.210.200 D13.695.201.200.270 D13.695.740.850.210.200
|
| Concept/Terms |
Fluorodeoxyuridylate- Fluorodeoxyuridylate
- 5-Fluoro-2'-Deoxyuridine-5'-Monophosphate
- 5 Fluoro 2' Deoxyuridine 5' Monophosphate
- FdUMP
|
Below are MeSH descriptors whose meaning is more general than "Fluorodeoxyuridylate".
Below are MeSH descriptors whose meaning is more specific than "Fluorodeoxyuridylate".
This graph shows the total number of publications written about "Fluorodeoxyuridylate" by people in this website by year, and whether "Fluorodeoxyuridylate" was a major or minor topic of these publications.
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Below are the most recent publications written about "Fluorodeoxyuridylate" by people in Profiles.
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Priest DG, Bunni MA, Romero-Fredes LR, Schmitz JC, Whiteley JM. A sensitive radioenzymatic assay for (S)-5-formyltetrahydrofolate. Anal Biochem. 1991 Aug 01; 196(2):284-9.
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Scanlon KJ, Newman EM, Lu Y, Priest DG. Biochemical basis for cisplatin and 5-fluorouracil synergism in human ovarian carcinoma cells. Proc Natl Acad Sci U S A. 1986 Dec; 83(23):8923-5.
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Priest DG, Doig MT. Tissue folate polyglutamate chain length determination by electrophoresis as thymidylate synthase-fluorodeoxyuridylate ternary complexes. Methods Enzymol. 1986; 122:313-9.
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Priest DG, Doig MT. Evaluation of folylpolyglutamates by electrophoretic separation of fluorodeoxyuridylate-thymidylate synthase-methylenetetrahydrofolate complexes. Adv Exp Med Biol. 1983; 163:139-48.
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Priest DG, Mangum M. Relative affinity of 5,10-methylenetetrahydrofolylpolyglutamates for the Lactobacillus casei thymidylate synthetase-5-fluorodeoxyuridylate binary complex. Arch Biochem Biophys. 1981 Aug; 210(1):118-23.
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Priest DG, Happel KK, Mangum M, Bednarek JM, Doig MT, Baugh CM. Tissue folylpolyglutamate chain-length characterization by electrophoresis as thymidylate synthetase-fluorodeoxyuridylate ternary complexes. Anal Biochem. 1981 Jul 15; 115(1):163-9.
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Priest DG, Alford CW, Batson KK, Doig MT. A centrifugal column assay for thymidylate synthetase using the active site titrant 5-fluoro-2'-deoxyuridylate. Anal Biochem. 1980 Mar 15; 103(1):51-4.