"Tetrahydrofolates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds based on 5,6,7,8-tetrahydrofolate.
| Descriptor ID |
D013763
|
| MeSH Number(s) |
D03.633.100.733.631.400.800 D08.211.840
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Tetrahydrofolates".
Below are MeSH descriptors whose meaning is more specific than "Tetrahydrofolates".
This graph shows the total number of publications written about "Tetrahydrofolates" by people in this website by year, and whether "Tetrahydrofolates" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 |
| 1995 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tetrahydrofolates" by people in Profiles.
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Aldh1l2 knockout mouse metabolomics links the loss of the mitochondrial folate enzyme to deregulation of a lipid metabolism observed in rare human disorder. Hum Genomics. 2020 11 09; 14(1):41.
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Cytosolic 10-formyltetrahydrofolate dehydrogenase regulates glycine metabolism in mouse liver. Sci Rep. 2019 10 17; 9(1):14937.
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A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance. J Biol Chem. 1998 Nov 13; 273(46):30189-98.
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Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells. Adv Enzyme Regul. 1997; 37:59-76.
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Multifactorial resistance to 5,10-dideazatetrahydrofolic acid in cell lines derived from human lymphoblastic leukemia CCRF-CEM. Cancer Res. 1995 Feb 01; 55(3):566-73.
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Impact of dietary folic acid on reduced folates in mouse plasma and tissues. Relationship to dideazatetrahydrofolate sensitivity. Biochem Pharmacol. 1994 Jul 19; 48(2):319-25.
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Disposition of folic acid and its metabolites: a comparison with leucovorin. Clin Pharmacol Ther. 1994 May; 55(5):501-8.
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5-methyltetrahydrofolate urinary excretion: modeling by cultured human kidney cells. Adv Exp Med Biol. 1993; 338:745-8.
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Folate metabolites as modulators of antitumor drug activity. Adv Exp Med Biol. 1993; 338:693-8.
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Altered transport of folic acid and antifolates through the carrier mediated reduced folate transport system in a human leukemia cell line resistant to (6R) 5,10-dideazatetrahydrofolic acid (DDATHF). Adv Exp Med Biol. 1993; 338:775-8.