"Receptors, Scavenger" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large group of structurally diverse cell surface receptors that mediate endocytic uptake of modified LIPOPROTEINS. Scavenger receptors are expressed by MYELOID CELLS and some ENDOTHELIAL CELLS, and were originally characterized based on their ability to bind acetylated LOW-DENSITY LIPOPROTEINS. They can also bind a variety of other polyanionic ligand. Certain scavenger receptors can internalize micro-organisms as well as apoptotic cells.
| Descriptor ID |
D051116
|
| MeSH Number(s) |
D12.776.543.750.705.940 D12.776.543.750.710.450.750
|
| Concept/Terms |
Receptors, Scavenger- Receptors, Scavenger
- Acetyl-LDL Receptors
- Acetyl LDL Receptors
- Receptors, Acetyl-LDL
- Scavenger Receptors
- Receptor, Acetyl-LDL
- Receptor, Acetyl LDL
- Scavenger Receptor
- Receptor, Scavenger
- Acetyl-LDL Receptor
- Acetyl LDL Receptor
- Acetylated LDL Receptor
- LDL Receptor, Acetylated
- Receptor, Acetylated LDL
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Scavenger".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Scavenger".
This graph shows the total number of publications written about "Receptors, Scavenger" by people in this website by year, and whether "Receptors, Scavenger" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
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Below are the most recent publications written about "Receptors, Scavenger" by people in Profiles.
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Liou B, Haffey WD, Greis KD, Grabowski GA. The LIMP-2/SCARB2 binding motif on acid ß-glucosidase: basic and applied implications for Gaucher disease and associated neurodegenerative diseases. J Biol Chem. 2014 Oct 24; 289(43):30063-74.
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Fu D, Yu JY, Wu M, Du M, Chen Y, Abdelsamie SA, Li Y, Chen J, Boulton ME, Ma JX, Lopes-Virella MF, Virella G, Lyons TJ. Immune complex formation in human diabetic retina enhances toxicity of oxidized LDL towards retinal capillary pericytes. J Lipid Res. 2014 May; 55(5):860-9.
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Kraml PJ, Klein RL, Huang Y, Nareika A, Lopes-Virella MF. Iron loading increases cholesterol accumulation and macrophage scavenger receptor I expression in THP-1 mononuclear phagocytes. Metabolism. 2005 Apr; 54(4):453-9.
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Webb NR, Cai L, Ziemba KS, Yu J, Kindy MS, van der Westhuyzen DR, de Beer FC. The fate of HDL particles in vivo after SR-BI-mediated selective lipid uptake. J Lipid Res. 2002 Nov; 43(11):1890-8.
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Webb NR, de Beer MC, Yu J, Kindy MS, Daugherty A, van der Westhuyzen DR, de Beer FC. Overexpression of SR-BI by adenoviral vector promotes clearance of apoA-I, but not apoB, in human apoB transgenic mice. J Lipid Res. 2002 Sep; 43(9):1421-8.
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Gowen BB, Borg TK, Ghaffar A, Mayer EP. The collagenous domain of class A scavenger receptors is involved in macrophage adhesion to collagens. J Leukoc Biol. 2001 Apr; 69(4):575-82.
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Smith JL, Schaffner AE, Hofmeister JK, Hartman M, Wei G, Forsthoefel D, Hume DA, Ostrowski MC. ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice. Mol Cell Biol. 2000 Nov; 20(21):8026-34.
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Gowen BB, Borg TK, Ghaffar A, Mayer EP. Selective adhesion of macrophages to denatured forms of type I collagen is mediated by scavenger receptors. Matrix Biol. 2000 Feb; 19(1):61-71.
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Lyons TJ, Li W, Wells-Knecht MC, Jokl R. Toxicity of mildly modified low-density lipoproteins to cultured retinal capillary endothelial cells and pericytes. Diabetes. 1994 Sep; 43(9):1090-5.