Glioblastoma

"Glioblastoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Descriptor ID	D005909
MeSH Number(s)	C04.557.465.625.600.380.080.335 C04.557.470.670.380.080.335 C04.557.580.625.600.380.080.335
Concept/Terms	Glioblastoma Glioblastoma Glioblastomas Astrocytoma, Grade IV Astrocytomas, Grade IV Grade IV Astrocytoma Grade IV Astrocytomas Glioblastoma Multiforme Glioblastoma Multiforme Giant Cell Glioblastoma Giant Cell Glioblastoma Giant Cell Glioblastomas Glioblastoma, Giant Cell Glioblastomas, Giant Cell

Below are MeSH descriptors whose meaning is more general than "Glioblastoma".

Diseases [C]
Neoplasms [C04]
Neoplasms by Histologic Type [C04.557]
Neoplasms, Germ Cell and Embryonal [C04.557.465]
Neuroectodermal Tumors [C04.557.465.625]
Neoplasms, Neuroepithelial [C04.557.465.625.600]
Glioma [C04.557.465.625.600.380]
Astrocytoma [C04.557.465.625.600.380.080]
Glioblastoma [C04.557.465.625.600.380.080.335]
Neoplasms, Glandular and Epithelial [C04.557.470]
Neoplasms, Neuroepithelial [C04.557.470.670]
Glioma [C04.557.470.670.380]
Astrocytoma [C04.557.470.670.380.080]
Glioblastoma [C04.557.470.670.380.080.335]
Neoplasms, Nerve Tissue [C04.557.580]
Neuroectodermal Tumors [C04.557.580.625]
Neoplasms, Neuroepithelial [C04.557.580.625.600]
Glioma [C04.557.580.625.600.380]
Astrocytoma [C04.557.580.625.600.380.080]
Glioblastoma [C04.557.580.625.600.380.080.335]

Below are MeSH descriptors whose meaning is related to "Glioblastoma".

Below are MeSH descriptors whose meaning is more specific than "Glioblastoma".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Glioblastoma" by people in this website by year, and whether "Glioblastoma" was a major or minor topic of these publications.

Bar chart showing 131 publications over 23 distinct years, with a maximum of 13 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1995	1	0	1
1997	1	0	1
2002	0	1	1
2004	1	0	1
2005	5	0	5
2006	1	2	3
2007	11	1	12
2008	7	1	8
2009	3	1	4
2010	6	1	7
2011	6	3	9
2012	4	0	4
2013	12	1	13
2014	7	1	8
2015	9	0	9
2016	7	2	9
2017	5	0	5
2018	7	0	7
2019	6	1	7
2020	9	1	10
2021	3	0	3
2022	3	0	3

Below are the most recent publications written about "Glioblastoma" by people in Profiles.

Kreatsoulas D, Bolyard C, Wu BX, Cam H, Giglio P, Li Z. Translational landscape of glioblastoma immunotherapy for physicians: guiding clinical practice with basic scientific evidence. J Hematol Oncol. 2022 06 11; 15(1):80.

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Das A, Gunasekaran A, Stephens HR, Mark J, Lindhorst SM, Cachia D, Patel SJ, Frankel BM. Establishing a Standardized Method for the Effective Intraoperative Collection and Biological Preservation of Brain Tumor Tissue Samples Using a Novel Tissue Preservation System: A Pilot Study. World Neurosurg. 2022 05; 161:e61-e74.

View in: PubMed
Perlow HK, Yaney A, Yang M, Klamer B, Matsui J, Raval RR, Blakaj DM, Arnett A, Beyer S, Elder JB, Ammirati M, Lonser R, Hardesty D, Ong S, Giglio P, Pillainayagam C, Goranovich J, Grecula J, Chakravarti A, Gondi V, Brown PD, Palmer JD. Dose-escalated accelerated hypofractionation for elderly or frail patients with a newly diagnosed glioblastoma. J Neurooncol. 2022 Jan; 156(2):399-406.

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Manea AJ, Ray SK. Regulation of autophagy as a therapeutic option in glioblastoma. Apoptosis. 2021 12; 26(11-12):574-599.

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Al-Sammarraie N, Ray SK. Applications of CRISPR-Cas9 Technology to Genome Editing in Glioblastoma Multiforme. Cells. 2021 09 07; 10(9).

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Frankel BM, Cachia D, Patel SJ, Das A. Analysis of the P53N a Novel Protein Encoded on Chromosome 22q12.1-12.3 in Glioblastomas and Ependymomas Specimens. J Mol Neurosci. 2021 Aug; 71(8):1714-1722.

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Gwak SJ, Che L, Yun Y, Lee M, Ha Y. Combination Therapy by Tissue-Specific Suicide Gene and Bevacizumab in Intramedullary Spinal Cord Tumor. Yonsei Med J. 2020 Dec; 61(12):1042-1049.

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Puduvalli VK, Wu J, Yuan Y, Armstrong TS, Vera E, Wu J, Xu J, Giglio P, Colman H, Walbert T, Raizer J, Groves MD, Tran D, Iwamoto F, Avgeropoulos N, Paleologos N, Fink K, Peereboom D, Chamberlain M, Merrell R, Penas Prado M, Yung WKA, Gilbert MR. A Bayesian adaptive randomized phase II multicenter trial of bevacizumab with or without vorinostat in adults with recurrent glioblastoma. Neuro Oncol. 2020 10 14; 22(10):1505-1515.

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Rahman M, Sawyer WG, Lindhorst S, Deleyrolle LP, Harrison JK, Karachi A, Dastmalchi F, Flores-Toro J, Mitchell DA, Lim M, Gilbert MR, Reardon DA. Adult immuno-oncology: using past failures to inform the future. Neuro Oncol. 2020 09 29; 22(9):1249-1261.

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Das A, Alshareef M, Porto GBF, Infinger LK, Vandergrift WA, Lindhorst SM, Varma AK, Patel SJ, Cachia D. Preconditioning with INC280 and LDK378 drugs sensitizes MGMT-unmethylated glioblastoma to temozolomide: Pre-clinical assessment. J Neurol Sci. 2020 Nov 15; 418:117102.

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