"Autophagy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The segregation and degradation of cytoplasmic constituents by AUTOPHAGOSOMES and their digestion by LYSOSOMES. It plays an important role in BIOLOGICAL METAMORPHOSIS and in the removal of bone by OSTEOCLASTS. Defective autophagy is associated with various diseases, including NEURODEGENERATIVE DISEASES and cancer.
| Descriptor ID |
D001343
|
| MeSH Number(s) |
G04.146.399 G04.417.350.091
|
| Concept/Terms |
Autophagy- Autophagy
- Autophagies
- Macro-autophagy
- Macro autophagy
- Macro-autophagies
- Autophagy, Cellular
- Autophagies, Cellular
- Cellular Autophagies
- Cellular Autophagy
- Macroautophagy
- Macroautophagies
- Autophagocytosis
Programmed Cell Death, Type II- Programmed Cell Death, Type II
- Autophagic Cell Death
- Autophagic Cell Deaths
- Cell Death, Autophagic
- Cell Deaths, Autophagic
- Death, Autophagic Cell
- Deaths, Autophagic Cell
- Autophagic Programmed Cell Death
|
Below are MeSH descriptors whose meaning is more general than "Autophagy".
Below are MeSH descriptors whose meaning is more specific than "Autophagy".
This graph shows the total number of publications written about "Autophagy" by people in this website by year, and whether "Autophagy" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 2 | 0 | 2 |
| 2002 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 2 | 1 | 3 |
| 2007 | 4 | 0 | 4 |
| 2008 | 1 | 0 | 1 |
| 2009 | 3 | 1 | 4 |
| 2010 | 8 | 6 | 14 |
| 2011 | 5 | 3 | 8 |
| 2012 | 6 | 5 | 11 |
| 2013 | 13 | 2 | 15 |
| 2014 | 7 | 4 | 11 |
| 2015 | 6 | 6 | 12 |
| 2016 | 10 | 3 | 13 |
| 2017 | 5 | 4 | 9 |
| 2018 | 3 | 5 | 8 |
| 2019 | 3 | 0 | 3 |
| 2020 | 3 | 4 | 7 |
| 2021 | 3 | 4 | 7 |
| 2022 | 1 | 6 | 7 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Autophagy" by people in Profiles.
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PFKP: More than phosphofructokinase. Adv Cancer Res. 2023; 160:1-15.
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Depletion of COPI in cancer cells: the role of reactive oxygen species in the induction of lipid accumulation, noncanonical lipophagy and apoptosis. Mol Biol Cell. 2022 12 01; 33(14):ar135.
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The Interplay Between Autophagy and Regulated Necrosis. Antioxid Redox Signal. 2023 03; 38(7-9):550-580.
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Use of acidic nanoparticles to rescue macrophage lysosomal dysfunction in atherosclerosis. Autophagy. 2023 03; 19(3):886-903.
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Autophagy and the Bone Marrow Microenvironment: A Review of Protective Factors in the Development and Maintenance of Multiple Myeloma. Front Immunol. 2022; 13:889954.
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Carbon Monoxide Activates PERK-Regulated Autophagy to Induce Immunometabolic Reprogramming and Boost Antitumor T-cell Function. Cancer Res. 2022 05 16; 82(10):1969-1990.
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Autophagy modulating therapeutics inhibit ovarian cancer colony generation by polyploid giant cancer cells (PGCCs). BMC Cancer. 2022 Apr 14; 22(1):410.
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Mitochondrial depolarization after acute ethanol treatment drives mitophagy in living mice. Autophagy. 2022 11; 18(11):2671-2685.
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Regulation of autophagy as a therapeutic option in glioblastoma. Apoptosis. 2021 12; 26(11-12):574-599.
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Substrate Reduction Therapy Reverses Mitochondrial, mTOR, and Autophagy Alterations in a Cell Model of Gaucher Disease. Cells. 2021 09 02; 10(9).