"Fenretinide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at risk of developing contralateral breast cancer. It is also effective as an antineoplastic agent.
| Descriptor ID |
D017313
|
| MeSH Number(s) |
D02.455.326.271.665.202.495.270 D02.455.426.392.368.367.379.249.700.270 D02.455.849.131.495.270 D23.767.261.700.270
|
| Concept/Terms |
Fenretinide- Fenretinide
- N-(4-Hydroxyphenyl)-trans-Retinamide
- Fenretinimide
- N-(4-Hydroxyphenyl)retinamide
- 4-HPR
- 4-Hydroxyphenylretinamide
- 4 Hydroxyphenylretinamide
|
Below are MeSH descriptors whose meaning is more general than "Fenretinide".
Below are MeSH descriptors whose meaning is more specific than "Fenretinide".
This graph shows the total number of publications written about "Fenretinide" by people in this website by year, and whether "Fenretinide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 1 | 2 |
| 2010 | 2 | 0 | 2 |
| 2011 | 4 | 0 | 4 |
| 2012 | 3 | 1 | 4 |
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Fenretinide" by people in Profiles.
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Synergism of 4HPR and SAHA increases anti-tumor actions in glioblastoma cells. Apoptosis. 2020 04; 25(3-4):217-232.
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Fumonisin B1 Inhibits Endoplasmic Reticulum Stress Associated-apoptosis After FoscanPDT Combined with C6-Pyridinium Ceramide or Fenretinide. Anticancer Res. 2017 02; 37(2):455-463.
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Enhanced apoptotic cancer cell killing after Foscan photodynamic therapy combined with fenretinide via de novo sphingolipid biosynthesis pathway. J Photochem Photobiol B. 2016 Jun; 159:191-5.
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Fenretinide inhibited de novo ceramide synthesis and proinflammatory cytokines induced by Aggregatibacter actinomycetemcomitans. J Lipid Res. 2013 Jan; 54(1):189-201.
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BCDO2 acts as a carotenoid scavenger and gatekeeper for the mitochondrial apoptotic pathway. Development. 2012 Aug; 139(16):2966-77.
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Dihydroceramide accumulation and reactive oxygen species are distinct and nonessential events in 4-HPR-mediated leukemia cell death. Biochem Cell Biol. 2012 Apr; 90(2):209-23.
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Alterations in expression of specific microRNAs by combination of 4-HPR and EGCG inhibited growth of human malignant neuroblastoma cells. Brain Res. 2012 May 15; 1454:1-13.
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Evaluation of bioactive sphingolipids in 4-HPR-resistant leukemia cells. BMC Cancer. 2011 Nov 07; 11:477.
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Synergistic efficacy of a novel combination therapy controls growth of Bcl-x(L) bountiful neuroblastoma cells by increasing differentiation and apoptosis. Cancer Biol Ther. 2011 Nov 01; 12(9):846-54.
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Combination of N-(4-hydroxyphenyl) retinamide and apigenin suppressed starvation-induced autophagy and promoted apoptosis in malignant neuroblastoma cells. Neurosci Lett. 2011 Sep 08; 502(1):24-9.