RNA, Antisense

"RNA, Antisense" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

RNA molecules which hybridize to complementary sequences in either RNA or DNA altering the function of the latter. Endogenous antisense RNAs function as regulators of gene expression by a variety of mechanisms. Synthetic antisense RNAs are used to effect the functioning of specific genes for investigative or therapeutic purposes.

Descriptor ID	D016372
MeSH Number(s)	D13.150.650 D13.444.600.150.760 D13.444.735.150 D27.720.470.530.600.150.760
Concept/Terms	RNA, Antisense RNA, Antisense Antisense RNA Anti-Sense RNA Anti Sense RNA RNA, Anti-Sense

Below are MeSH descriptors whose meaning is more general than "RNA, Antisense".

Chemicals and Drugs [D]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Antisense Elements (Genetics) [D13.150]
RNA, Antisense [D13.150.650]
Nucleic Acids [D13.444]
Nucleic Acid Probes [D13.444.600]
Antisense Elements (Genetics) [D13.444.600.150]
RNA, Antisense [D13.444.600.150.760]
RNA [D13.444.735]
RNA, Antisense [D13.444.735.150]
Chemical Actions and Uses [D27]
Specialty Uses of Chemicals [D27.720]
Laboratory Chemicals [D27.720.470]
Molecular Probes [D27.720.470.530]
Nucleic Acid Probes [D27.720.470.530.600]
Antisense Elements (Genetics) [D27.720.470.530.600.150]
RNA, Antisense [D27.720.470.530.600.150.760]

Below are MeSH descriptors whose meaning is related to "RNA, Antisense".

Below are MeSH descriptors whose meaning is more specific than "RNA, Antisense".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "RNA, Antisense" by people in this website by year, and whether "RNA, Antisense" was a major or minor topic of these publications.

Bar chart showing 14 publications over 10 distinct years, with a maximum of 3 publications in 1998

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	0	2	2
1995	1	0	1
1998	0	3	3
1999	1	0	1
2000	1	0	1
2003	1	0	1
2005	1	1	2
2006	0	1	1
2010	0	1	1
2012	0	1	1

Below are the most recent publications written about "RNA, Antisense" by people in Profiles.

Yan M, Hall JW, Yang J, Ji Y. The essential yhcSR two-component signal transduction system directly regulates the lac and opuCABCD operons of Staphylococcus aureus. PLoS One. 2012; 7(11):e50608.

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Grillo CA, Piroli GG, Evans AN, Macht VA, Wilson SP, Scott KA, Sakai RR, Mott DD, Reagan LP. Obesity/hyperleptinemic phenotype adversely affects hippocampal plasticity: effects of dietary restriction. Physiol Behav. 2011 Aug 03; 104(2):235-41.

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Primeaux SD, Wilson SP, Bray GA, York DA, Wilson MA. Overexpression of neuropeptide Y in the central nucleus of the amygdala decreases ethanol self-administration in "anxious" rats. Alcohol Clin Exp Res. 2006 May; 30(5):791-801.

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Yan Y, Rubinchik S, Wood AL, Gillanders WE, Dong JY, Watson DK, Cole DJ. Bystander effect contributes to the antitumor efficacy of CaSm antisense gene therapy in a preclinical model of advanced pancreatic cancer. Mol Ther. 2006 Feb; 13(2):357-65.

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Fraser MM, Watson PM, Fraig MM, Kelley JR, Nelson PS, Boylan AM, Cole DJ, Watson DK. CaSm-mediated cellular transformation is associated with altered gene expression and messenger RNA stability. Cancer Res. 2005 Jul 15; 65(14):6228-36.

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Toren A, Rozenfeld-Granot G, Heath KE, Amariglio N, Rocca B, Crosson J, Epstein CJ, Laghi F, Landolfi R, Carlsson LE, Argraves S, Bizzaro N, Moxey-Mims M, Brok-Simoni F, Martignetti JA, Greinacher A, Rechavi G. MYH9 spectrum of autosomal-dominant giant platelet syndromes: unexpected association with fibulin-1 variant-D inactivation. Am J Hematol. 2003 Dec; 74(4):254-62.

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Kelley JR, Fraser MM, Hubbard JM, Watson DK, Cole DJ. CaSm antisense gene therapy: a novel approach for the treatment of pancreatic cancer. Anticancer Res. 2003 May-Jun; 23(3A):2007-13.

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Kelley JR, Brown JM, Frasier MM, Baron PL, Schweinfest CW, Vournakis JN, Watson DK, Cole DJ. The cancer-associated Sm-like oncogene: a novel target for the gene therapy of pancreatic cancer. Surgery. 2000 Aug; 128(2):353-60.

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Refolo LM, Eckman C, Prada CM, Yager D, Sambamurti K, Mehta N, Hardy J, Younkin SG. Antisense-induced reduction of presenilin 1 expression selectively increases the production of amyloid beta42 in transfected cells. J Neurochem. 1999 Dec; 73(6):2383-8.

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Sementchenko VI, Schweinfest CW, Papas TS, Watson DK. ETS2 function is required to maintain the transformed state of human prostate cancer cells. Oncogene. 1998 Dec 03; 17(22):2883-8.

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