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Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles.

Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles. Nat Cell Biol. 2015 Aug; 17(8):1036-48.

View in: PubMed

subject areas
  • Animals
  • Binding Sites
  • Cell Cycle Checkpoints
  • Cell Proliferation
  • Chromatin Assembly and Disassembly
  • E2F Transcription Factors
  • E2F1 Transcription Factor
  • E2F2 Transcription Factor
  • E2F3 Transcription Factor
  • Epithelial Cells
  • Female
  • G1 Phase Cell Cycle Checkpoints
  • G2 Phase Cell Cycle Checkpoints
  • Gene Expression Regulation
  • Genotype
  • Intestine, Small
  • Male
  • Mice, 129 Strain
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Phenotype
  • Promoter Regions, Genetic
  • Proto-Oncogene Proteins c-myc
  • Retinoblastoma Protein
  • S Phase Cell Cycle Checkpoints
  • Signal Transduction
  • Time Factors
  • Transcription, Genetic

authors with profiles
  • Gustavo Leone
  • Christopher S Koivisto