E2F2 Transcription Factor
"E2F2 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A. E2F2 activates GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis.
| Descriptor ID |
D050703
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| MeSH Number(s) |
D12.776.930.211.625
|
| Concept/Terms |
E2F2 Transcription Factor- E2F2 Transcription Factor
- Transcription Factor, E2F2
- Transcription Factor E2F-2
- E2F-2, Transcription Factor
- Transcription Factor E2F 2
- E2F Transcription Factor 2 Protein
- E2F2 Protein
- E2F-2 Protein
|
Below are MeSH descriptors whose meaning is more general than "E2F2 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "E2F2 Transcription Factor".
This graph shows the total number of publications written about "E2F2 Transcription Factor" by people in this website by year, and whether "E2F2 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 3 | 1 | 4 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 3 | 3 |
| 2010 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "E2F2 Transcription Factor" by people in Profiles.
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Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs. Mol Cell. 2019 06 20; 74(6):1264-1277.e7.
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Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles. Nat Cell Biol. 2015 Aug; 17(8):1036-48.
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The E2F2 transcription factor sustains hepatic glycerophospholipid homeostasis in mice. PLoS One. 2014; 9(11):e112620.
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Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis. Oncogene. 2015 Jan 02; 34(1):119-28.
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Canonical and atypical E2Fs regulate the mammalian endocycle. Nat Cell Biol. 2012 Nov; 14(11):1192-202.
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Cell proliferation in the absence of E2F1-3. Dev Biol. 2011 Mar 01; 351(1):35-45.
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E2f1-3 are critical for myeloid development. J Biol Chem. 2011 Feb 11; 286(6):4783-95.
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Division and apoptosis of E2f-deficient retinal progenitors. Nature. 2009 Dec 17; 462(7275):925-9.
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E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells. Nature. 2009 Dec 17; 462(7275):930-4.
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E2F3 is a mediator of DNA damage-induced apoptosis. Mol Cell Biol. 2010 Jan; 30(2):524-36.