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Applied stretch initiates directional invasion through the action of Rap1 GTPase as a tension sensor.

Applied stretch initiates directional invasion through the action of Rap1 GTPase as a tension sensor. J Cell Sci. 2017 01 01; 130(1):152-163.

View in: PubMed

subject areas
  • Actins
  • Animals
  • Biomechanical Phenomena
  • Cell Aggregation
  • Cell Line, Tumor
  • Cell Proliferation
  • Collagen
  • Crk-Associated Substrate Protein
  • Extracellular Matrix
  • Focal Adhesions
  • Gels
  • Guanosine Triphosphate
  • Humans
  • Integrins
  • Intercellular Junctions
  • Mice
  • Neoplasm Invasiveness
  • Phosphatidylinositol 3-Kinases
  • Phosphatidylinositol Phosphates
  • Phosphorylation
  • Polymerization
  • Protein Stability
  • Pseudopodia
  • rac1 GTP-Binding Protein
  • rap1 GTP-Binding Proteins
  • Signal Transduction
  • Stress, Mechanical
  • Vinculin

authors with profiles
  • Michael R. Gold