"Vinculin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytoskeletal protein associated with cell-cell and cell-matrix interactions. The amino acid sequence of human vinculin has been determined. The protein consists of 1066 amino acid residues and its gene has been assigned to chromosome 10.
| Descriptor ID |
D016596
|
| MeSH Number(s) |
D12.776.220.990
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Vinculin".
Below are MeSH descriptors whose meaning is more specific than "Vinculin".
This graph shows the total number of publications written about "Vinculin" by people in this website by year, and whether "Vinculin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 1 | 2 |
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Vinculin" by people in Profiles.
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Characterization of focal adhesion proteins in rodent hepatic stellate cells. Histochem Cell Biol. 2022 Oct; 158(4):325-334.
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Applied stretch initiates directional invasion through the action of Rap1 GTPase as a tension sensor. J Cell Sci. 2017 01 01; 130(1):152-163.
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Cardiac aging: Send in the vinculin reinforcements. Sci Transl Med. 2015 Jun 17; 7(292):292fs26.
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Effects of elevated glucose levels on interactions of cardiac fibroblasts with the extracellular matrix. In Vitro Cell Dev Biol Anim. 2007 Sep-Oct; 43(8-9):297-305.
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Focal complex formation in adult cardiomyocytes is accompanied by the activation of beta3 integrin and c-Src. J Mol Cell Cardiol. 2003 Jun; 35(6):671-83.
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Myofibrillogenesis and formation of cell contacts mediate the localization of N-RAP in cultured chick cardiomyocytes. Cell Motil Cytoskeleton. 2000 Sep; 47(1):63-76.
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Mechanical forces regulate focal adhesion and costamere assembly in cardiac myocytes. Am J Physiol. 1997 Aug; 273(2 Pt 2):H546-56.
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Vinculin is an essential component for normal myofibrillar arrangement in fetal mouse cardiac myocytes. J Mol Cell Cardiol. 1997 Aug; 29(8):2041-52.
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The role of beta 1 integrin in spreading and myofibrillogenesis in neonatal rat cardiomyocytes in vitro. Cell Motil Cytoskeleton. 1992; 21(2):87-100.
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Myofibrillar and cytoskeletal assembly in neonatal rat cardiac myocytes cultured on laminin and collagen. Cell Tissue Res. 1991 Jun; 264(3):577-87.