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Efficacy of a glutathione S-transferase pi-activated prodrug in platinum-resistant ovarian cancer cells.

Efficacy of a glutathione S-transferase pi-activated prodrug in platinum-resistant ovarian cancer cells. Mol Cancer Ther. 2002 Oct; 1(12):1089-95.

View in: PubMed

subject areas
  • Antigens, Nuclear
  • Catalytic Domain
  • Cell Survival
  • Chromatography, High Pressure Liquid
  • Cisplatin
  • Cytotoxins
  • Dimerization
  • DNA Helicases
  • DNA-Activated Protein Kinase
  • DNA-Binding Proteins
  • Dose-Response Relationship, Drug
  • Doxorubicin
  • Drug Resistance, Neoplasm
  • Electrophoresis, Polyacrylamide Gel
  • Enzyme Activation
  • Female
  • Glutathione
  • Glutathione S-Transferase pi
  • Glutathione Transferase
  • Humans
  • Immunoblotting
  • Inhibitory Concentration 50
  • Isoenzymes
  • Ku Autoantigen
  • Models, Chemical
  • Nuclear Proteins
  • Ovarian Neoplasms
  • Precipitin Tests
  • Prodrugs
  • Reverse Transcriptase Polymerase Chain Reaction
  • Time Factors
  • Tumor Cells, Cultured

authors with profiles
  • Kenneth D. Tew
  • Danyelle Townsend