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RANKL coordinates cell cycle withdrawal and differentiation in osteoclasts through the cyclin-dependent kinase inhibitors p27KIP1 and p21CIP1.

RANKL coordinates cell cycle withdrawal and differentiation in osteoclasts through the cyclin-dependent kinase inhibitors p27KIP1 and p21CIP1. J Bone Miner Res. 2004 Aug; 19(8):1339-48.

View in: PubMed

subject areas
  • Acid Phosphatase
  • Alkaline Phosphatase
  • Animals
  • Blotting, Western
  • Bone Marrow Cells
  • Carrier Proteins
  • Cathepsin K
  • Cathepsins
  • CDC2-CDC28 Kinases
  • Cell Cycle
  • Cell Cycle Proteins
  • Cell Differentiation
  • Cell Proliferation
  • Cells, Cultured
  • Chromones
  • Cyclin-Dependent Kinase 2
  • Cyclin-Dependent Kinase Inhibitor p18
  • Cyclin-Dependent Kinase Inhibitor p19
  • Cyclin-Dependent Kinase Inhibitor p21
  • Cyclin-Dependent Kinase Inhibitor p27
  • Enzyme Inhibitors
  • Femur
  • Flavonoids
  • Gene Expression
  • Imidazoles
  • Isoenzymes
  • Macrophage Colony-Stimulating Factor
  • Macrophages
  • Membrane Glycoproteins
  • Mice
  • Mice, Inbred C57BL
  • Mice, Knockout
  • Morpholines
  • Osteoclasts
  • Osteopetrosis
  • Pyridines
  • Radiography
  • RANK Ligand
  • Receptor Activator of Nuclear Factor-kappa B
  • Reverse Transcriptase Polymerase Chain Reaction
  • Tartrate-Resistant Acid Phosphatase
  • Tumor Suppressor Proteins

authors with profiles
  • Michael C Ostrowski