RANKL coordinates cell cycle withdrawal and differentiation in osteoclasts through the cyclin-dependent kinase inhibitors p27KIP1 and p21CIP1.

RANKL coordinates cell cycle withdrawal and differentiation in osteoclasts through the cyclin-dependent kinase inhibitors p27KIP1 and p21CIP1. J Bone Miner Res. 2004 Aug; 19(8):1339-48.

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subject areas

Acid Phosphatase
Alkaline Phosphatase
Animals
Blotting, Western
Bone Marrow Cells
Carrier Proteins
Cathepsin K
Cathepsins
CDC2-CDC28 Kinases
Cell Cycle
Cell Cycle Proteins
Cell Differentiation
Cell Proliferation
Cells, Cultured
Chromones
Cyclin-Dependent Kinase 2
Cyclin-Dependent Kinase Inhibitor p18
Cyclin-Dependent Kinase Inhibitor p19
Cyclin-Dependent Kinase Inhibitor p21
Cyclin-Dependent Kinase Inhibitor p27
Enzyme Inhibitors
Femur
Flavonoids
Gene Expression
Imidazoles
Isoenzymes
Macrophage Colony-Stimulating Factor
Macrophages
Membrane Glycoproteins
Mice
Mice, Inbred C57BL
Mice, Knockout
Morpholines
Osteoclasts
Osteopetrosis
Pyridines
Radiography
RANK Ligand
Receptor Activator of Nuclear Factor-kappa B
Reverse Transcriptase Polymerase Chain Reaction
Tartrate-Resistant Acid Phosphatase
Tumor Suppressor Proteins

authors with profiles

Michael C Ostrowski