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    • Primary peripheral T cells become susceptible to 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated apoptosis in vitro upon activation and in the presence of dendritic cells.
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    • A Screen Using iPSC-Derived Hepatocytes Reveals NAD+ as a Potential Treatment for mtDNA Depletion Syndrome.
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A Screen Using iPSC-Derived Hepatocytes Reveals NAD+ as a Potential Treatment for mtDNA Depletion Syndrome.

A Screen Using iPSC-Derived Hepatocytes Reveals NAD+ as a Potential Treatment for mtDNA Depletion Syndrome. Cell Rep. 2018 11 06; 25(6):1469-1484.e5.

View in: PubMed

subject areas
  • Adenosine Triphosphate
  • Animals
  • Base Sequence
  • Cell Differentiation
  • Cell Respiration
  • DNA, Mitochondrial
  • Female
  • Glucose
  • Glycolysis
  • Hepatocytes
  • Humans
  • Induced Pluripotent Stem Cells
  • Male
  • Mitochondria
  • Mutation
  • NAD
  • Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
  • Phosphotransferases (Alcohol Group Acceptor)
  • Rats
  • Ribonucleotide Reductases
  • Syndrome

authors with profiles
  • John J. Lemasters
  • Craig Cano Beeson
  • Stephen Alexander Duncan
  • James Corbett