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The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168.
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The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168.
The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168. Nat Cell Biol. 2018 03; 20(3):320-331.
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PubMed
subject areas
A549 Cells
AMP-Activated Protein Kinases
Animals
Cell Proliferation
DNA Breaks, Double-Stranded
DNA Repair
Female
HCT116 Cells
HEK293 Cells
Humans
Male
Mechanistic Target of Rapamycin Complex 1
Mice
Mice, Inbred BALB C
Mice, Nude
Mice, Transgenic
Neoplasms
Phosphorylation
Ribosomal Protein S6 Kinases, 70-kDa
Ribosomal Protein S6 Kinases, 90-kDa
Signal Transduction
TOR Serine-Threonine Kinases
Tumor Burden
Ubiquitin-Protein Ligases
authors with profiles
Wenjian Gan