"Necrosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. It is distinct it from APOPTOSIS, which is a normal, regulated cellular process.
| Descriptor ID |
D009336
|
| MeSH Number(s) |
C23.550.717 G04.146.638
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Necrosis".
Below are MeSH descriptors whose meaning is more specific than "Necrosis".
This graph shows the total number of publications written about "Necrosis" by people in this website by year, and whether "Necrosis" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 4 | 4 |
| 1995 | 1 | 1 | 2 |
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 2 | 2 |
| 1998 | 1 | 4 | 5 |
| 1999 | 2 | 4 | 6 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 7 | 7 |
| 2003 | 2 | 10 | 12 |
| 2004 | 0 | 5 | 5 |
| 2005 | 1 | 6 | 7 |
| 2006 | 1 | 4 | 5 |
| 2007 | 1 | 8 | 9 |
| 2008 | 0 | 10 | 10 |
| 2009 | 1 | 3 | 4 |
| 2010 | 0 | 6 | 6 |
| 2011 | 0 | 9 | 9 |
| 2012 | 1 | 5 | 6 |
| 2013 | 0 | 5 | 5 |
| 2014 | 1 | 9 | 10 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 3 | 3 |
| 2017 | 1 | 3 | 4 |
| 2018 | 1 | 4 | 5 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 2 | 2 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 3 | 3 |
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Below are the most recent publications written about "Necrosis" by people in Profiles.
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The Interplay Between Autophagy and Regulated Necrosis. Antioxid Redox Signal. 2023 03; 38(7-9):550-580.
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Platanosides, a Potential Botanical Drug Combination, Decrease Liver Injury Caused by Acetaminophen Overdose in Mice. J Nat Prod. 2022 07 22; 85(7):1779-1788.
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The Spike Protein of SARS-CoV-2 Impairs Lipid Metabolism and Increases Susceptibility to Lipotoxicity: Implication for a Role of Nrf2. Cells. 2022 06 14; 11(12).
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pH-responsive and folate-coated liposomes encapsulating irinotecan as an alternative to improve efficacy of colorectal cancer treatment. Biomed Pharmacother. 2021 Dec; 144:112317.
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An Animal Trial on the Optimal Time and Intensity of Exercise after Stroke. Med Sci Sports Exerc. 2020 08; 52(8):1699-1709.
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The in vivo biocompatibility of novel tannic acid-collagen type I injectable bead scaffold material for breast reconstruction post-lumpectomy. J Biomater Appl. 2020 04; 34(9):1315-1329.
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Aldehyde dehydrogenase-2 activation by Alda-1 decreases necrosis and fibrosis after bile duct ligation in mice. Free Radic Biol Med. 2019 12; 145:136-145.
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Receptor-interacting Ser/Thr kinase 1 (RIPK1) and myosin IIA-dependent ceramidosomes form membrane pores that mediate blebbing and necroptosis. J Biol Chem. 2019 01 11; 294(2):502-519.
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Types of naming errors in chronic post-stroke aphasia are dissociated by dual stream axonal loss. Sci Rep. 2018 09 25; 8(1):14352.
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Lipopolysaccharide-induced necroptosis of brain microvascular endothelial cells can be prevented by inhibition of endothelin receptors. Physiol Res. 2018 06 27; 67(Suppl 1):S227-S236.