Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
"Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subgroup of cyclic nucleotide-regulated ION CHANNELS of the superfamily of pore-loop cation channels that are opened by hyperpolarization rather than depolarization. The ion conducting pore passes SODIUM, CALCIUM, and POTASSIUM cations with a preference for potassium.
| Descriptor ID |
D064428
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| MeSH Number(s) |
D12.776.157.530.400.368 D12.776.543.550.450.476 D12.776.543.585.400.476
|
| Concept/Terms |
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels- Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
- Hyperpolarization Activated Cyclic Nucleotide Gated Channels
- Ih Cation Channels
- Cation Channels, Ih
- Channels, Ih Cation
- Hyperpolarization Cyclic-Nucleotide Gated Ion Channels
- Hyperpolarization Cyclic Nucleotide Gated Ion Channels
- I(h) Channels
- Hyperpolarization-Activated Cation Channel
- Cation Channel, Hyperpolarization-Activated
- Channel, Hyperpolarization-Activated Cation
- Hyperpolarization Activated Cation Channel
- HCN Pacemaker Channels
- Channels, HCN Pacemaker
- Pacemaker Channels, HCN
- I(h) Cation Channels
HCN4 Channel- HCN4 Channel
- Channel, HCN4
- Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 4
- Hyperpolarization Cyclic Nucleotide Gated Cation Channel 4
HCN3 Channel- HCN3 Channel
- Channel, HCN3
- Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 3
- Hyperpolarization Cyclic Nucleotide Gated Cation Channel 3
HCN1 Channel- HCN1 Channel
- Channel, HCN1
- Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 1
- Hyperpolarization Cyclic Nucleotide Gated Cation Channel 1
HCN2 Channel- HCN2 Channel
- Channel, HCN2
- Potassium-Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2
- Potassium Sodium Hyperpolarization Activated Cyclic Nucleotide Gated Channel 2
- HCN2 Potassium Channel
- Channel, HCN2 Potassium
- Potassium Channel, HCN2
- Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2
- Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 2
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Below are MeSH descriptors whose meaning is more general than "Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels".
Below are MeSH descriptors whose meaning is more specific than "Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels".
This graph shows the total number of publications written about "Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels" by people in this website by year, and whether "Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels" by people in Profiles.
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Morad M, Zhang XH. Mechanisms of spontaneous pacing: sinoatrial nodal cells, neonatal cardiomyocytes, and human stem cell derived cardiomyocytes. Can J Physiol Pharmacol. 2017 Oct; 95(10):1100-1107.
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Harris BS, Baicu CF, Haghshenas N, Kasiganesan H, Scholz D, Rackley MS, Miquerol L, Gros D, Mukherjee R, O'Brien TX. Remodeling of the peripheral cardiac conduction system in response to pressure overload. Am J Physiol Heart Circ Physiol. 2012 Apr 15; 302(8):H1712-25.
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Carr DB, Andrews GD, Glen WB, Lavin A. alpha2-Noradrenergic receptors activation enhances excitability and synaptic integration in rat prefrontal cortex pyramidal neurons via inhibition of HCN currents. J Physiol. 2007 Oct 15; 584(Pt 2):437-50.