Transient Receptor Potential Channels
"Transient Receptor Potential Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with SENSATION is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a DROSOPHILA mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. ANKYRIN REPEATS are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with TYROSINE KINASE or TYPE C PHOSPHOLIPASES.
| Descriptor ID |
D050051
|
| MeSH Number(s) |
D12.776.157.530.400.901 D12.776.543.585.400.901
|
| Concept/Terms |
Transient Receptor Potential Channels- Transient Receptor Potential Channels
- TRP Membrane Proteins
- Membrane Proteins, TRP
- Proteins, TRP Membrane
- TRP Cation Channels
- Cation Channels, TRP
- Channels, TRP Cation
- Transient Receptor Potential Cation Channels
|
Below are MeSH descriptors whose meaning is more general than "Transient Receptor Potential Channels".
Below are MeSH descriptors whose meaning is more specific than "Transient Receptor Potential Channels".
This graph shows the total number of publications written about "Transient Receptor Potential Channels" by people in this website by year, and whether "Transient Receptor Potential Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transient Receptor Potential Channels" by people in Profiles.
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The Calcineurin-TFEB-p62 Pathway Mediates the Activation of Cardiac Macroautophagy by Proteasomal Malfunction. Circ Res. 2020 07 31; 127(4):502-518.
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Tear gas: an epidemiological and mechanistic reassessment. Ann N Y Acad Sci. 2016 08; 1378(1):96-107.
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Pancreatic pain. Curr Opin Gastroenterol. 2015 Sep; 31(5):407-15.
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Mucolipidosis type IV: a subtle pediatric neurodegenerative disorder. Pediatr Neurol. 2010 Mar; 42(3):223-6.
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Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function. J Neurosci. 2008 Oct 01; 28(40):10102-10.