Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
"Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subgroup of cyclic nucleotide-regulated ION CHANNELS of the superfamily of pore-loop cation channels that are opened by hyperpolarization rather than depolarization. The ion conducting pore passes SODIUM, CALCIUM, and POTASSIUM cations with a preference for potassium.
| Descriptor ID |
D064428
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| MeSH Number(s) |
D12.776.157.530.400.368 D12.776.543.550.450.476 D12.776.543.585.400.476
|
| Concept/Terms |
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels- Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
- Hyperpolarization Activated Cyclic Nucleotide Gated Channels
- Ih Cation Channels
- Cation Channels, Ih
- Channels, Ih Cation
- Hyperpolarization Cyclic-Nucleotide Gated Ion Channels
- Hyperpolarization Cyclic Nucleotide Gated Ion Channels
- I(h) Channels
- Hyperpolarization-Activated Cation Channel
- Cation Channel, Hyperpolarization-Activated
- Channel, Hyperpolarization-Activated Cation
- Hyperpolarization Activated Cation Channel
- HCN Pacemaker Channels
- Channels, HCN Pacemaker
- Pacemaker Channels, HCN
- I(h) Cation Channels
HCN4 Channel- HCN4 Channel
- Channel, HCN4
- Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 4
- Hyperpolarization Cyclic Nucleotide Gated Cation Channel 4
HCN3 Channel- HCN3 Channel
- Channel, HCN3
- Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 3
- Hyperpolarization Cyclic Nucleotide Gated Cation Channel 3
HCN1 Channel- HCN1 Channel
- Channel, HCN1
- Hyperpolarization Cyclic-Nucleotide Gated Cation Channel 1
- Hyperpolarization Cyclic Nucleotide Gated Cation Channel 1
HCN2 Channel- HCN2 Channel
- Channel, HCN2
- Potassium-Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2
- Potassium Sodium Hyperpolarization Activated Cyclic Nucleotide Gated Channel 2
- HCN2 Potassium Channel
- Channel, HCN2 Potassium
- Potassium Channel, HCN2
- Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2
- Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 2
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Below are MeSH descriptors whose meaning is more general than "Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels".
Below are MeSH descriptors whose meaning is more specific than "Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels".
This graph shows the total number of publications written about "Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels" by people in this website by year, and whether "Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels" by people in Profiles.
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Mechanisms of spontaneous pacing: sinoatrial nodal cells, neonatal cardiomyocytes, and human stem cell derived cardiomyocytes. Can J Physiol Pharmacol. 2017 Oct; 95(10):1100-1107.
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Remodeling of the peripheral cardiac conduction system in response to pressure overload. Am J Physiol Heart Circ Physiol. 2012 Apr 15; 302(8):H1712-25.
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alpha2-Noradrenergic receptors activation enhances excitability and synaptic integration in rat prefrontal cortex pyramidal neurons via inhibition of HCN currents. J Physiol. 2007 Oct 15; 584(Pt 2):437-50.