"Lumican" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A small leucine-rich proteoglycan that contains 10 tandem leucine repeats and four N-linked sites within the leucine repeat region that may be substituted with KERATAN SULFATE. These properties and its horseshoe shape allow it to mediate interactions among COLLAGEN molecules within fibrils. It is expressed in most mesenchymal tissues as well as the CORNEA, where it functions to maintain transparency.
Below are MeSH descriptors whose meaning is more general than "Lumican".
Below are MeSH descriptors whose meaning is more specific than "Lumican".
This graph shows the total number of publications written about "Lumican" by people in this website by year, and whether "Lumican" was a major or minor topic of these publications.
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Below are the most recent publications written about "Lumican" by people in Profiles.
Dupuis LE, Doucette L, Rice AK, Lancaster AE, Berger MG, Chakravarti S, Kern CB. Development of myotendinous-like junctions that anchor cardiac valves requires fibromodulin and lumican. Dev Dyn. 2016 10; 245(10):1029-42.
Dupuis LE, Berger MG, Feldman S, Doucette L, Fowlkes V, Chakravarti S, Thibaudeau S, Alcala NE, Bradshaw AD, Kern CB. Lumican deficiency results in cardiomyocyte hypertrophy with altered collagen assembly. J Mol Cell Cardiol. 2015 Jul; 84:70-80.
Markiewicz M, Asano Y, Znoyko S, Gong Y, Watson DK, Trojanowska M. Distinct effects of gonadectomy in male and female mice on collagen fibrillogenesis in the skin. J Dermatol Sci. 2007 Sep; 47(3):217-26.
Munyer PD, Schulte BA. Immunohistochemical identification of proteoglycans in gelatinous membranes of cat and gerbil inner ear. Hear Res. 1991 Apr; 52(2):369-78.