"Decorin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A small leucine-rich proteoglycan that interacts with FIBRILLAR COLLAGENS and modifies the EXTRACELLULAR MATRIX structure of CONNECTIVE TISSUE. Decorin has also been shown to play additional roles in the regulation of cellular responses to GROWTH FACTORS. The protein contains a single glycosaminoglycan chain and is similar in structure to BIGLYCAN.
| Descriptor ID |
D058575
|
| MeSH Number(s) |
D09.698.735.700.750 D12.776.395.650.750.625 D12.776.395.650.875.500 D12.776.860.300.806.750
|
| Concept/Terms |
Decorin- Decorin
- Bone Proteoglycan II
- Proteoglycan II, Bone
- DSPG-II
|
Below are MeSH descriptors whose meaning is more general than "Decorin".
Below are MeSH descriptors whose meaning is more specific than "Decorin".
This graph shows the total number of publications written about "Decorin" by people in this website by year, and whether "Decorin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Decorin" by people in Profiles.
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Lumican deficiency results in cardiomyocyte hypertrophy with altered collagen assembly. J Mol Cell Cardiol. 2015 Jul; 84:70-80.
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A role for estrogen receptor-a and estrogen receptor-? in collagen biosynthesis in mouse skin. J Invest Dermatol. 2013 Jan; 133(1):120-7.
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Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1. J Neurosci Res. 2008 Dec; 86(16):3515-25.
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Distinct effects of gonadectomy in male and female mice on collagen fibrillogenesis in the skin. J Dermatol Sci. 2007 Sep; 47(3):217-26.