"Kallikrein-Kinin System" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A system of metabolic interactions by products produced in the distal nephron of the KIDNEY. These products include KALLIKREIN; KININS; KININASE I; KININASE II; and ENKEPHALINASE. This system participates in the control of renal functions. It interacts with the RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM to regulate BLOOD PRESSURE, generation of PROSTAGLANDINS, release of VASOPRESSINS, and WATER-ELECTROLYTE BALANCE.
| Descriptor ID |
D016234
|
| MeSH Number(s) |
G02.111.635.500.500 G03.493.485 G03.615.500.500 G07.410.810.500.500 G09.330.380.690
|
| Concept/Terms |
Kallikrein-Kinin System- Kallikrein-Kinin System
- Kallikrein Kinin System
- Kallikrein-Kinin Systems
- Systems, Kallikrein-Kinin
|
Below are MeSH descriptors whose meaning is more general than "Kallikrein-Kinin System".
Below are MeSH descriptors whose meaning is more specific than "Kallikrein-Kinin System".
This graph shows the total number of publications written about "Kallikrein-Kinin System" by people in this website by year, and whether "Kallikrein-Kinin System" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Kallikrein-Kinin System" by people in Profiles.
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Savitt AG, Manimala S, White T, Fandaros M, Yin W, Duan H, Xu X, Geisbrecht BV, Rubenstein DA, Kaplan AP, Peerschke EI, Ghebrehiwet B. SARS-CoV-2 Exacerbates COVID-19 Pathology Through Activation of the Complement and Kinin Systems. Front Immunol. 2021; 12:767347.
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Madkhali H, Tarawneh A, Ali Z, Le HV, Cutler SJ, Khan IA, Shariat-Madar Z. Identification of Human Kinin-Forming Enzyme Inhibitors from Medicinal Herbs. Molecules. 2021 Jul 07; 26(14).
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Nokkari A, Abou-El-Hassan H, Mechref Y, Mondello S, Kindy MS, Jaffa AA, Kobeissy F. Implication of the Kallikrein-Kinin system in neurological disorders: Quest for potential biomarkers and mechanisms. Prog Neurobiol. 2018 Jun - Aug; 165-167:26-50.
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Nokkari A, Mouhieddine TH, Itani MM, Abou-Kheir W, Daoud G, Zhu R, Mechref Y, Meshref Y, Soueid J, Al Hariri M, Mondello S, Jaffa AA, Kobeissy F. Characterization of the Kallikrein-Kinin System Post Chemical Neuronal Injury: An In Vitro Biochemical and Neuroproteomics Assessment. PLoS One. 2015; 10(6):e0128601.
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Webb JG, Yang X, Crosson CE. Expression of the kallikrein/kinin system in human anterior segment. Exp Eye Res. 2009 Aug; 89(2):126-32.
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Chao J, Bledsoe G, Yin H, Chao L. The tissue kallikrein-kinin system protects against cardiovascular and renal diseases and ischemic stroke independently of blood pressure reduction. Biol Chem. 2006 Jun; 387(6):665-75.
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Agata J, Chao L, Chao J. Kallikrein gene delivery improves cardiac reserve and attenuates remodeling after myocardial infarction. Hypertension. 2002 Nov; 40(5):653-9.
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Joseph K, Shibayama Y, Ghebrehiwet B, Kaplan AP. Factor XII-dependent contact activation on endothelial cells and binding proteins gC1qR and cytokeratin 1. Thromb Haemost. 2001 Jan; 85(1):119-24.
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Murakami H, Yayama K, Miao RQ, Wang C, Chao L, Chao J. Kallikrein gene delivery inhibits vascular smooth muscle cell growth and neointima formation in the rat artery after balloon angioplasty. Hypertension. 1999 Aug; 34(2):164-70.
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Chao J, Chao L. Kallikrein gene therapy: a new strategy for hypertensive diseases. Immunopharmacology. 1997 Jun; 36(2-3):229-36.