von Willebrand Factor

"von Willebrand Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.

Descriptor ID	D014841
MeSH Number(s)	D12.776.124.125.920 D23.119.985
Concept/Terms	von Willebrand Factor von Willebrand Factor Factor VIIIR-Ag Factor VIIIR Ag Factor VIIIR-RCo Factor VIIIR RCo Ristocetin-Willebrand Factor Ristocetin Willebrand Factor von Willebrand Protein Factor VIII-Related Antigen Factor VIII Related Antigen Ristocetin Cofactor Plasma Factor VIII Complex Plasma Factor VIII Complex

Below are MeSH descriptors whose meaning is more general than "von Willebrand Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Blood Coagulation Factors [D12.776.124.125]
von Willebrand Factor [D12.776.124.125.920]
Biological Factors [D23]
Blood Coagulation Factors [D23.119]
von Willebrand Factor [D23.119.985]

Below are MeSH descriptors whose meaning is more specific than "von Willebrand Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "von Willebrand Factor" by people in this website by year, and whether "von Willebrand Factor" was a major or minor topic of these publications.

Bar chart showing 20 publications over 16 distinct years, with a maximum of 2 publications in 1995 and 2002 and 2014 and 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	0	1	1
1994	0	1	1
1995	2	0	2
1996	0	1	1
2001	0	1	1
2002	1	1	2
2004	0	1	1
2005	1	0	1
2006	0	1	1
2009	0	1	1
2012	0	1	1
2014	2	0	2
2015	0	2	2
2017	1	0	1
2020	1	0	1
2021	0	1	1

Below are the most recent publications written about "von Willebrand Factor" by people in Profiles.

Vijayalekshmi B, Sharma A, Prabhu SB, Nair SC, Mammen J, Goel A, Zachariah UG, Dutta AK, Balasubramanian KA, Elias E, Eapen CE. Reticuloendothelial activation correlates with disease severity and predicts mortality in severe alcoholic hepatitis. Eur J Gastroenterol Hepatol. 2021 12 01; 33(1S Suppl 1):e329-e334.

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Sardar D, Mathews N, Mammen J, Nair SC, Jacob S, Patel L, Thomas A, Jhanwar S, Sharma A, Sen M, Vijayalekshmi B, Balasubramanian KA, Subramani K, Thomas L, Abhilash KPP, Zachariah U, Elias E, Goel A, Eapen CE. Rodenticidal hepatotoxicity: Raised plasma Von Willebrand factor levels predict in-hospital survival and preliminary report of the outcome of Von Willebrand factor reducing management protocol. Indian J Gastroenterol. 2019 12; 38(6):527-533.

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Tobin WO, Kinsella JA, Kavanagh GF, O'Donnell JS, McGrath RT, Tierney S, Egan B, Feeley TM, Coughlan T, Collins DR, O'Neill D, Murphy S, Lim SJ, Murphy RP, McCabe D. Profile of von Willebrand factor antigen and von Willebrand factor propeptide in an overall TIA and ischaemic stroke population and amongst subtypes. J Neurol Sci. 2017 Apr 15; 375:404-410.

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Hyacinth HI, Adams RJ, Greenberg CS, Voeks JH, Hill A, Hibbert JM, Gee BE. Effect of Chronic Blood Transfusion on Biomarkers of Coagulation Activation and Thrombin Generation in Sickle Cell Patients at Risk for Stroke. PLoS One. 2015; 10(8):e0134193.

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Kidder W, Nguyen S, Larios J, Bergstrom J, Ceponis A, von Drygalski A. Point-of-care musculoskeletal ultrasound is critical for the diagnosis of hemarthroses, inflammation and soft tissue abnormalities in adult patients with painful haemophilic arthropathy. Haemophilia. 2015 Jul; 21(4):530-7.

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Tobin WO, Kinsella JA, Kavanagh GF, O'Donnell JS, McGrath RT, Coughlan T, Collins DR, O'Neill D, Egan B, Tierney S, Feeley TM, Murphy RP, McCabe DJ. Longitudinal assessment of von Willebrand factor antigen and von Willebrand factor propeptide in response to alteration of antiplatelet therapy after TIA or ischaemic stroke. J Neurol. 2014 Jul; 261(7):1405-12.

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Blenner MA, Dong X, Springer TA. Structural basis of regulation of von Willebrand factor binding to glycoprotein Ib. J Biol Chem. 2014 Feb 28; 289(9):5565-79.

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Huber AJ, Aberle T, Schleicher M, Wendel HP, Brockbank KG. Characterization of a simplified ice-free cryopreservation method for heart valves. Cell Tissue Bank. 2013 Jun; 14(2):195-203.

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Sellers MB, Tricoci P, Harrington RA. A new generation of antiplatelet agents. Curr Opin Cardiol. 2009 Jul; 24(4):307-12.

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Cho SW, Jeon O, Lim JE, Gwak SJ, Kim SS, Choi CY, Kim DI, Kim BS. Preliminary experience with tissue engineering of a venous vascular patch by using bone marrow-derived cells and a hybrid biodegradable polymer scaffold. J Vasc Surg. 2006 Dec; 44(6):1329-40.

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