"Factor XIII" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fibrin-stabilizing plasma enzyme (TRANSGLUTAMINASES) that is activated by THROMBIN and CALCIUM to form FACTOR XIIIA. It is important for stabilizing the formation of the fibrin polymer (clot) which culminates the coagulation cascade.
| Descriptor ID |
D005176
|
| MeSH Number(s) |
D12.776.124.125.475 D23.119.475
|
| Concept/Terms |
Factor XIII- Factor XIII
- Factor Thirteen
- Coagulation Factor XIII
- Factor XIII, Coagulation
- XIII, Coagulation Factor
- Factor XIII Transamidase
- Transamidase, Factor XIII
- Fibrinase
- Laki Lorand Factor
- Laki-Lorand Factor
- Blood Coagulation Factor XIII
- Factor 13
- Fibrin Stabilizing Factor
- Stabilizing Factor, Fibrin
|
Below are MeSH descriptors whose meaning is more general than "Factor XIII".
Below are MeSH descriptors whose meaning is more specific than "Factor XIII".
This graph shows the total number of publications written about "Factor XIII" by people in this website by year, and whether "Factor XIII" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 1 | 2 |
| 2002 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Factor XIII" by people in Profiles.
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Biology of Factor XIII and clinical manifestations of Factor XIII deficiency. Transfusion. 2013 May; 53(5):1120-31.
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Spontaneous splenic rupture in a patient with factor XIII deficiency and a novel mutation. Pediatr Blood Cancer. 2008 Jan; 50(1):113-4.
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Roles of transglutaminases in cardiac and vascular diseases. Front Biosci. 2007 Jan 01; 12:2530-45.
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Role of factor XIII in fibrin clot formation and effects of genetic polymorphisms. Blood. 2002 Aug 01; 100(3):743-54.
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Analysis of factor XIII substrate specificity using recombinant human factor XIII and tissue transglutaminase chimeras. J Biol Chem. 1997 Oct 03; 272(40):25149-56.
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Sphingosylphosphocholine reduces the calcium ion requirement for activating tissue transglutaminase. J Biol Chem. 1997 Jun 27; 272(26):16295-300.
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C-terminal deletion of human tissue transglutaminase enhances magnesium-dependent GTP/ATPase activity. J Biol Chem. 1996 Dec 06; 271(49):31191-5.
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A microtiter plate assay for factor XIII A-chain-fibrin interactions. Anal Biochem. 1994 May 15; 219(1):43-8.
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Purification and characterization of recombinant human coagulant factor XIII A-chains expressed in E. coli. Protein Expr Purif. 1994 Apr; 5(2):125-32.
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A microtiter plate transglutaminase assay utilizing 5-(biotinamido)pentylamine as substrate. Anal Biochem. 1992 Aug 15; 205(1):166-71.