Cholinesterase Inhibitors
"Cholinesterase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
Descriptor ID |
D002800
|
MeSH Number(s) |
D27.505.519.389.275 D27.505.519.625.120.300 D27.505.696.577.120.300
|
Concept/Terms |
Cholinesterase Inhibitors- Cholinesterase Inhibitors
- Inhibitors, Cholinesterase
- Anticholinesterase Drugs
- Drugs, Anticholinesterase
- Anticholinesterases
- Anticholinesterase Agents
- Agents, Anticholinesterase
- Anti-Cholinesterases
- Anti Cholinesterases
|
Below are MeSH descriptors whose meaning is more general than "Cholinesterase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Cholinesterase Inhibitors".
This graph shows the total number of publications written about "Cholinesterase Inhibitors" by people in this website by year, and whether "Cholinesterase Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 1 | 0 | 1 |
2001 | 2 | 0 | 2 |
2002 | 1 | 0 | 1 |
2003 | 4 | 0 | 4 |
2004 | 1 | 3 | 4 |
2005 | 6 | 0 | 6 |
2006 | 1 | 3 | 4 |
2007 | 2 | 1 | 3 |
2008 | 1 | 0 | 1 |
2009 | 0 | 2 | 2 |
2010 | 0 | 2 | 2 |
2011 | 0 | 2 | 2 |
2014 | 3 | 2 | 5 |
2015 | 1 | 1 | 2 |
2016 | 1 | 0 | 1 |
2017 | 2 | 3 | 5 |
2018 | 0 | 1 | 1 |
2020 | 1 | 0 | 1 |
2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cholinesterase Inhibitors" by people in Profiles.
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Rivastigmine Transdermal Patch Treatment for Moderate to Severe Cognitive Impairment in Veterans with Traumatic Brain Injury (RiVET Study): A Randomized Clinical Trial. J Neurotrauma. 2021 07 15; 38(14):1943-1952.
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Effects on Postoperative Gastrointestinal Motility After Neuromuscular Blockade Reversal With Sugammadex Versus Neostigmine/Glycopyrrolate in Colorectal Surgery Patients. Ann Pharmacother. 2020 12; 54(12):1165-1174.
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Ogilvie's syndrome: management and outcomes. Medicine (Baltimore). 2018 Jul; 97(27):e11187.
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Pyridostigmine for the Reversal of Severe Adverse Reactions to Botulinum Toxin in Children. J Pediatr. 2018 03; 194:241-243.
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Anti-inflammatory Dimeric 2-(2-Phenylethyl)chromones from the Resinous Wood of Aquilaria sinensis. J Nat Prod. 2018 03 23; 81(3):543-553.
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Brief isoflurane administration as a post-exposure treatment for organophosphate poisoning. Neurotoxicology. 2017 Dec; 63:84-89.
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Ascorbic acid tethered polymeric nanoparticles enable efficient brain delivery of galantamine: An in vitro-in vivo study. Sci Rep. 2017 09 11; 7(1):11086.
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Strength of cholinergic tone dictates the polarity of dopamine D2 receptor modulation of striatal cholinergic interneuron excitability in DYT1 dystonia. Exp Neurol. 2017 Sep; 295:162-175.
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Synthesis and biological evaluation of ranitidine analogs as multiple-target-directed cognitive enhancers for the treatment of Alzheimer's disease. Bioorg Med Chem Lett. 2016 11 15; 26(22):5573-5579.
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Diisopropylfluorophosphate Impairs the Transport of Membrane-Bound Organelles in Rat Cortical Axons. J Pharmacol Exp Ther. 2016 Mar; 356(3):645-55.