Matrix Metalloproteinase 12
"Matrix Metalloproteinase 12" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A secreted matrix metalloproteinase which is highly expressed by MACROPHAGES where it may play a role in INFLAMMATION and WOUND HEALING.
| Descriptor ID |
D053508
|
| MeSH Number(s) |
D08.811.277.656.300.480.525.700.500 D08.811.277.656.675.374.525.700.500 D12.644.276.848.500 D12.776.467.836.500
|
| Concept/Terms |
Matrix Metalloproteinase 12- Matrix Metalloproteinase 12
- Metalloproteinase 12, Matrix
- Macrophage-Specific Metalloelastase
- Macrophage Specific Metalloelastase
- Metalloelastase, Macrophage-Specific
- MMP12 Metalloproteinase
- Metalloproteinase, MMP12
- MMP-12 Metalloproteinase
- MMP 12 Metalloproteinase
- Metalloproteinase, MMP-12
- Macrophage Metalloelastase
- Metalloelastase, Macrophage
- Metalloproteinase Elastase
- Elastase, Metalloproteinase
|
Below are MeSH descriptors whose meaning is more general than "Matrix Metalloproteinase 12".
Below are MeSH descriptors whose meaning is more specific than "Matrix Metalloproteinase 12".
This graph shows the total number of publications written about "Matrix Metalloproteinase 12" by people in this website by year, and whether "Matrix Metalloproteinase 12" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 4 | 4 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 7 | 7 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 1 | 2 |
| 2009 | 2 | 0 | 2 |
| 2011 | 1 | 1 | 2 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Matrix Metalloproteinase 12" by people in Profiles.
-
Matrix Metalloproteinase MMP-12 Promotes Macrophage Transmigration Across Intestinal Epithelial Tight Junctions and Increases Severity of Experimental Colitis. J Crohns Colitis. 2021 Oct 07; 15(10):1751-1765.
-
Targeted delivery of pentagalloyl glucose inhibits matrix metalloproteinase activity and preserves elastin in emphysematous lungs. Respir Res. 2021 Sep 18; 22(1):249.
-
Matrix Metalloproteinase-12 Is Required for Granuloma Progression. Front Immunol. 2020; 11:553949.
-
Hedging our bets. J Thorac Cardiovasc Surg. 2018 05; 155(5):2177-2178.
-
Macrophage Elastase Induces TRAIL-mediated Tumor Cell Death through Its Carboxy-Terminal Domain. Am J Respir Crit Care Med. 2017 08 01; 196(3):353-363.
-
Altered Expression Levels of MMP1, MMP9, MMP12, TIMP1, and IL-1? as a Risk Factor for the Elevated IOP and Optic Nerve Head Damage in the Primary Open-Angle Glaucoma Patients. Biomed Res Int. 2015; 2015:812503.
-
Macrophage elastase suppresses white adipose tissue expansion with cigarette smoking. Am J Respir Cell Mol Biol. 2014 Dec; 51(6):822-9.
-
A protean protease: MMP-12 fights viruses as a protease and a transcription factor. Nat Med. 2014 May; 20(5):470-2.
-
Evidence for early fibrosis and increased airway resistance in bone marrow transplant recipient mice deficient in MMP12. Am J Physiol Lung Cell Mol Physiol. 2011 Oct; 301(4):L519-26.
-
IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke. PLoS One. 2011; 6(5):e20333.