Pulmonary Surfactant-Associated Protein C
"Pulmonary Surfactant-Associated Protein C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pulmonary surfactant associated protein that plays a role in alveolar stability by lowering the surface tension at the air-liquid interface. It is a membrane-bound protein that constitutes 1-2% of the pulmonary surfactant mass. Pulmonary surfactant-associated protein C is one of the most hydrophobic peptides yet isolated and contains an alpha-helical domain with a central poly-valine segment that binds to phospholipid bilayers.
| Descriptor ID |
D037721
|
| MeSH Number(s) |
D12.776.543.717 D12.776.816.750 D12.776.823.186
|
| Concept/Terms |
Pulmonary Surfactant-Associated Protein C- Pulmonary Surfactant-Associated Protein C
- Pulmonary Surfactant Associated Protein C
- Surfactant Polypeptide SP-C
- SP-C, Surfactant Polypeptide
- Surfactant Polypeptide SP C
- SP-C protein
- SP C protein
- Pulmonary Surfactant Protein C
- Pulmonary Surfactant-Associated Protein SP-C
- Pulmonary Surfactant Associated Protein SP C
|
Below are MeSH descriptors whose meaning is more general than "Pulmonary Surfactant-Associated Protein C".
Below are MeSH descriptors whose meaning is more specific than "Pulmonary Surfactant-Associated Protein C".
This graph shows the total number of publications written about "Pulmonary Surfactant-Associated Protein C" by people in this website by year, and whether "Pulmonary Surfactant-Associated Protein C" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 2 | 0 | 2 |
| 2003 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Pulmonary Surfactant-Associated Protein C" by people in Profiles.
-
Glasser SW, Maxfield MD, Ruetschilling TL, Akinbi HT, Baatz JE, Kitzmiller JA, Page K, Xu Y, Bao EL, Korfhagen TR. Persistence of LPS-induced lung inflammation in surfactant protein-C-deficient mice. Am J Respir Cell Mol Biol. 2013 Nov; 49(5):845-54.
-
Grek CL, Newton DA, Spyropoulos DD, Baatz JE. Hypoxia up-regulates expression of hemoglobin in alveolar epithelial cells. Am J Respir Cell Mol Biol. 2011 Apr; 44(4):439-47.
-
Glasser SW, Witt TL, Senft AP, Baatz JE, Folger D, Maxfield MD, Akinbi HT, Newton DA, Prows DR, Korfhagen TR. Surfactant protein C-deficient mice are susceptible to respiratory syncytial virus infection. Am J Physiol Lung Cell Mol Physiol. 2009 Jul; 297(1):L64-72.
-
Dluhy RA, Shanmukh S, Leapard JB, Krüger P, Baatz JE. Deacylated pulmonary surfactant protein SP-C transforms from alpha-helical to amyloid fibril structure via a pH-dependent mechanism: an infrared structural investigation. Biophys J. 2003 Oct; 85(4):2417-29.
-
Krüger P, Baatz JE, Dluhy RA, Lösche M. Effect of hydrophobic surfactant protein SP-C on binary phospholipid monolayers. Molecular machinery at the air/water interface. Biophys Chem. 2002 Nov 06; 99(3):209-28.
-
Shanmukh S, Howell P, Baatz JE, Dluhy RA. Effect of hydrophobic surfactant proteins SP-B and SP-C on phospholipid monolayers. Protein structure studied using 2D IR and beta correlation analysis. Biophys J. 2002 Oct; 83(4):2126-41.