Receptor, Parathyroid Hormone, Type 1
"Receptor, Parathyroid Hormone, Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A parathyroid hormone receptor subtype that recognizes both PARATHYROID HORMONE and PARATHYROID HORMONE-RELATED PROTEIN. It is a G-protein-coupled receptor that is expressed at high levels in BONE and in KIDNEY.
| Descriptor ID |
D044168
|
| MeSH Number(s) |
D12.776.543.750.695.650.100 D12.776.543.750.750.600.100
|
| Concept/Terms |
Receptor, Parathyroid Hormone, Type 1- Receptor, Parathyroid Hormone, Type 1
- PTH-PTHrP Receptor
- PTH PTHrP Receptor
- Receptor, PTH-PTHrP
- PTH-Related Peptide Receptor
- PTH Related Peptide Receptor
- Receptor, PTH-Related Peptide
- PTH-Related Protein Receptor
- PTH Related Protein Receptor
- Receptor, PTH-Related Protein
- PTHLP Receptor
- Receptor, PTHLP
- PTHrP Receptor
- Receptor, PTHrP
- Parathyroid Hormone Receptor Type I
- Receptor, Parathyroid Hormone-Like Peptide
- Parathyroid Hormone-Like Peptide Receptor
- Parathyroid Hormone Like Peptide Receptor
- Parathyroid Hormone Receptor 1
- Parathyroid Hormone Receptor Type 1
- Parathyroid Hormone Receptor
- Receptor, Parathyroid Hormone
- Parathyroid Hormone-Related Peptide Receptor
- Parathyroid Hormone Related Peptide Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Parathyroid Hormone, Type 1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Parathyroid Hormone [D12.776.543.750.695.650]
- Receptor, Parathyroid Hormone, Type 1 [D12.776.543.750.695.650.100]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Parathyroid Hormone [D12.776.543.750.750.600]
- Receptor, Parathyroid Hormone, Type 1 [D12.776.543.750.750.600.100]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Parathyroid Hormone, Type 1".
This graph shows the total number of publications written about "Receptor, Parathyroid Hormone, Type 1" by people in this website by year, and whether "Receptor, Parathyroid Hormone, Type 1" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2015 | 0 | 3 | 3 |
| 2017 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Receptor, Parathyroid Hormone, Type 1" by people in Profiles.
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Luttrell LM, Maudsley S, Gesty-Palmer D. Translating in vitro ligand bias into in vivo efficacy. Cell Signal. 2018 01; 41:46-55.
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Williams GR, Bethard JR, Berkaw MN, Nagel AK, Luttrell LM, Ball LE. Exploring G protein-coupled receptor signaling networks using SILAC-based phosphoproteomics. Methods. 2016 Jan 01; 92:36-50.
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Maudsley S, Martin B, Janssens J, Etienne H, Jushaj A, van Gastel J, Willemsen A, Chen H, Gesty-Palmer D, Luttrell LM. Informatic deconvolution of biased GPCR signaling mechanisms from in vivo pharmacological experimentation. Methods. 2016 Jan 01; 92:51-63.
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Maudsley S, Martin B, Gesty-Palmer D, Cheung H, Johnson C, Patel S, Becker KG, Wood WH, Zhang Y, Lehrmann E, Luttrell LM. Delineation of a conserved arrestin-biased signaling repertoire in vivo. Mol Pharmacol. 2015 Apr; 87(4):706-17.
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Appleton KM, Luttrell LM. Emergent biological properties of arrestin pathway-selective biased agonism. J Recept Signal Transduct Res. 2013 Jun; 33(3):153-61.
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Leonard AP, Appleton KM, Luttrell LM, Peterson YK. A high-content, live-cell, and real-time approach to the quantitation of ligand-induced ß-Arrestin2 and Class A/Class B GPCR mobilization. Microsc Microanal. 2013 Feb; 19(1):150-70.
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Gesty-Palmer D, Luttrell LM. 'Biasing' the parathyroid hormone receptor: a novel anabolic approach to increasing bone mass? Br J Pharmacol. 2011 Sep; 164(1):59-67.
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Gesty-Palmer D, Flannery P, Yuan L, Corsino L, Spurney R, Lefkowitz RJ, Luttrell LM. A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation. Sci Transl Med. 2009 Oct 07; 1(1):1ra1.
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Gesty-Palmer D, Chen M, Reiter E, Ahn S, Nelson CD, Wang S, Eckhardt AE, Cowan CL, Spurney RF, Luttrell LM, Lefkowitz RJ. Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation. J Biol Chem. 2006 Apr 21; 281(16):10856-64.
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Sanada H, Jose PA, Hazen-Martin D, Yu PY, Xu J, Bruns DE, Phipps J, Carey RM, Felder RA. Dopamine-1 receptor coupling defect in renal proximal tubule cells in hypertension. Hypertension. 1999 Apr; 33(4):1036-42.