"Factor XIII" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fibrin-stabilizing plasma enzyme (TRANSGLUTAMINASES) that is activated by THROMBIN and CALCIUM to form FACTOR XIIIA. It is important for stabilizing the formation of the fibrin polymer (clot) which culminates the coagulation cascade.
| Descriptor ID |
D005176
|
| MeSH Number(s) |
D12.776.124.125.475 D23.119.475
|
| Concept/Terms |
Factor XIII- Factor XIII
- Factor Thirteen
- Coagulation Factor XIII
- Factor XIII, Coagulation
- XIII, Coagulation Factor
- Factor XIII Transamidase
- Transamidase, Factor XIII
- Fibrinase
- Laki Lorand Factor
- Laki-Lorand Factor
- Blood Coagulation Factor XIII
- Factor 13
- Fibrin Stabilizing Factor
- Stabilizing Factor, Fibrin
|
Below are MeSH descriptors whose meaning is more general than "Factor XIII".
Below are MeSH descriptors whose meaning is more specific than "Factor XIII".
This graph shows the total number of publications written about "Factor XIII" by people in this website by year, and whether "Factor XIII" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Factor XIII" by people in Profiles.
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Levy JH, Greenberg C. Biology of Factor XIII and clinical manifestations of Factor XIII deficiency. Transfusion. 2013 May; 53(5):1120-31.
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Khalife H, Muwakkit S, Al-Moussawi H, Dabbous I, Khoury R, Peyvandi F, Abboud MR. Spontaneous splenic rupture in a patient with factor XIII deficiency and a novel mutation. Pediatr Blood Cancer. 2008 Jan; 50(1):113-4.
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Sane DC, Kontos JL, Greenberg CS. Roles of transglutaminases in cardiac and vascular diseases. Front Biosci. 2007 Jan 01; 12:2530-45.
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Ariëns RA, Lai TS, Weisel JW, Greenberg CS, Grant PJ. Role of factor XIII in fibrin clot formation and effects of genetic polymorphisms. Blood. 2002 Aug 01; 100(3):743-54.
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Lai TS, Bielawska A, Peoples KA, Hannun YA, Greenberg CS. Sphingosylphosphocholine reduces the calcium ion requirement for activating tissue transglutaminase. J Biol Chem. 1997 Jun 27; 272(26):16295-300.
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Lai TS, Slaughter TF, Koropchak CM, Haroon ZA, Greenberg CS. C-terminal deletion of human tissue transglutaminase enhances magnesium-dependent GTP/ATPase activity. J Biol Chem. 1996 Dec 06; 271(49):31191-5.
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Achyuthan KE, Santiago MA, Greenberg CS. A microtiter plate assay for factor XIII A-chain-fibrin interactions. Anal Biochem. 1994 May 15; 219(1):43-8.
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Lai TS, Santiago MA, Achyuthan KE, Greenberg CS. Purification and characterization of recombinant human coagulant factor XIII A-chains expressed in E. coli. Protein Expr Purif. 1994 Apr; 5(2):125-32.
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Slaughter TF, Achyuthan KE, Lai TS, Greenberg CS. A microtiter plate transglutaminase assay utilizing 5-(biotinamido)pentylamine as substrate. Anal Biochem. 1992 Aug 15; 205(1):166-71.
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Greenberg CS, Birckbichler PJ, Rice RH. Transglutaminases: multifunctional cross-linking enzymes that stabilize tissues. FASEB J. 1991 Dec; 5(15):3071-7.