"beta-Lactams" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo-thiazine, and including monocyclic MONOBACTAMS. The BETA-LACTAMASES hydrolyze the beta lactam ring, accounting for BETA-LACTAM RESISTANCE of infective bacteria.
| Descriptor ID |
D047090
|
| MeSH Number(s) |
D02.065.589.099 D02.886.108 D03.633.100.300
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "beta-Lactams".
Below are MeSH descriptors whose meaning is more specific than "beta-Lactams".
This graph shows the total number of publications written about "beta-Lactams" by people in this website by year, and whether "beta-Lactams" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 4 | 1 | 5 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 2 | 2 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "beta-Lactams" by people in Profiles.
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Antipseudomonal treatment decisions during CF exacerbation management. J Cyst Fibros. 2022 09; 21(5):753-758.
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Alcaligenes faecalis metallo-?-lactamase in extensively drug-resistant Pseudomonas aeruginosa isolates. Clin Microbiol Infect. 2022 Jun; 28(6):880.e1-880.e8.
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Empirical fluoroquinolones versus broad-spectrum beta-lactams for Gram-negative bloodstream infections in the absence of antimicrobial resistance risk factors. J Glob Antimicrob Resist. 2020 09; 22:87-93.
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Role of Early De-escalation of Antimicrobial Therapy on Risk of Clostridioides difficile Infection Following Enterobacteriaceae Bloodstream Infections. Clin Infect Dis. 2019 07 18; 69(3):414-420.
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Risk factors for pneumonia due to beta-lactam-susceptible and beta-lactam-resistant Pseudomonas aeruginosa: a case-case-control study. Infection. 2018 Aug; 46(4):487-494.
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Methodology for Monobactam Diversification: Syntheses and Studies of 4-Thiomethyl Substituted ?-Lactams with Activity against Gram-Negative Bacteria, Including Carbapenemase Producing Acinetobacter baumannii. J Med Chem. 2017 11 09; 60(21):8933-8944.
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Penicillin-Binding Protein 3 Is Essential for Growth of Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2017 01; 61(1).
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Alternate "Drug" Delivery Utilizing ?-Lactam Cores: Syntheses and Biological Evaluation of ?-Lactams Bearing Isocyanate Precursors. J Org Chem. 2017 01 06; 82(1):737-744.
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Clinical Risk Score for Prediction of Extended-Spectrum ?-Lactamase-Producing Enterobacteriaceae in Bloodstream Isolates. Infect Control Hosp Epidemiol. 2017 03; 38(3):266-272.
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Differential effect of prior ?-lactams and fluoroquinolones on risk of bloodstream infections secondary to Pseudomonas aeruginosa. Diagn Microbiol Infect Dis. 2017 Jan; 87(1):87-91.