"Thiourea" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A photographic fixative used also in the manufacture of resins. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance may reasonably be anticipated to be a carcinogen (Merck Index, 9th ed). Many of its derivatives are ANTITHYROID AGENTS and/or FREE RADICAL SCAVENGERS.
| Descriptor ID |
D013890
|
| MeSH Number(s) |
D02.886.904 D02.948.898
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Thiourea".
Below are MeSH descriptors whose meaning is more specific than "Thiourea".
This graph shows the total number of publications written about "Thiourea" by people in this website by year, and whether "Thiourea" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2015 | 2 | 1 | 3 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thiourea" by people in Profiles.
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Another Weapon in the Battle against Idiopathic Pulmonary Fibrosis? Am J Respir Cell Mol Biol. 2019 Apr; 60(4):386-387.
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Influence of linker length and composition on enzymatic activity and ribosomal binding of neomycin dimers. Antimicrob Agents Chemother. 2015 Jul; 59(7):3899-905.
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Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures. Bioorg Med Chem. 2015 Apr 01; 23(7):1601-12.
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Interrogating alkyl and arylalkylpolyamino (bis)urea and (bis)thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum parasites. Bioorg Med Chem. 2015 Aug 15; 23(16):5131-43.
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Discovery of novel alkylated (bis)urea and (bis)thiourea polyamine analogues with potent antimalarial activities. J Med Chem. 2011 Oct 13; 54(19):6624-33.
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(Bis)urea and (bis)thiourea inhibitors of lysine-specific demethylase 1 as epigenetic modulators. J Med Chem. 2010 Jul 22; 53(14):5197-212.
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Amide isosteres of oroidin: assessment of antibiofilm activity and C. elegans toxicity. J Med Chem. 2009 Aug 13; 52(15):4582-5.
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Chronic administration of KB-R7943 induces up-regulation of cardiac NCX1. J Biol Chem. 2009 Oct 02; 284(40):27265-72.
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Solid-phase synthesis of oligomeric deoxynucleic-thiourea (DNT) and deoxynucleic S-methylthiourea (DNmt): a neutral/polycationic analogue of DNA. Bioorg Med Chem Lett. 2000 Apr 17; 10(8):691-3.
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Triple-helix formation of DNA oligomers with methylthiourea-linked nucleosides (DNmt): a kinetic and thermodynamic analysis. Proc Natl Acad Sci U S A. 1999 Apr 13; 96(8):4384-9.