"Methylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Addition of methyl groups. In histo-chemistry methylation is used to esterify carboxyl groups and remove sulfate groups by treating tissue sections with hot methanol in the presence of hydrochloric acid. (From Stedman, 25th ed)
Descriptor ID |
D008745
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MeSH Number(s) |
G02.111.035.538 G02.607.094.538 G03.059.538
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Methylation".
Below are MeSH descriptors whose meaning is more specific than "Methylation".
This graph shows the total number of publications written about "Methylation" by people in this website by year, and whether "Methylation" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 2 | 2 |
2005 | 0 | 2 | 2 |
2007 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
2010 | 0 | 2 | 2 |
2011 | 0 | 1 | 1 |
2012 | 0 | 4 | 4 |
2013 | 0 | 5 | 5 |
2014 | 0 | 3 | 3 |
2015 | 0 | 3 | 3 |
2016 | 0 | 2 | 2 |
2018 | 0 | 1 | 1 |
2019 | 0 | 4 | 4 |
2020 | 0 | 1 | 1 |
2021 | 0 | 2 | 2 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Methylation" by people in Profiles.
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The Role of Protein Arginine Methyltransferases in DNA Damage Response. Int J Mol Sci. 2022 Aug 29; 23(17).
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Structural basis for plazomicin antibiotic action and resistance. Commun Biol. 2021 06 11; 4(1):729.
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PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis. Nat Commun. 2021 06 08; 12(1):3444.
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Increased H3K4me3 methylation and decreased miR-7113-5p expression lead to enhanced Wnt/?-catenin signaling in immune cells from PTSD patients leading to inflammatory phenotype. Mol Med. 2020 11 14; 26(1):110.
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Cannabidiol Regulates Gene Expression in Encephalitogenic T cells Using Histone Methylation and noncoding RNA during Experimental Autoimmune Encephalomyelitis. Sci Rep. 2019 10 31; 9(1):15780.
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PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage. Cancer Discov. 2019 09; 9(9):1306-1323.
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Crystal Structure of GenD2, an NAD-Dependent Oxidoreductase Involved in the Biosynthesis of Gentamicin. ACS Chem Biol. 2019 05 17; 14(5):925-933.
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AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions. Nat Cell Biol. 2019 02; 21(2):226-237.
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Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer. Clin Cancer Res. 2018 12 15; 24(24):6433-6446.
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SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/?-Catenin and Hippo/YAP Signaling. Dev Cell. 2016 Apr 04; 37(1):47-57.