ADP-ribosyl Cyclase 1

"ADP-ribosyl Cyclase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A bifunctional enzyme that catalyzes the synthesis and HYDROLYSIS of CYCLIC ADP-RIBOSE (cADPR) from NAD+ to ADP-RIBOSE. It is a cell surface molecule which is predominantly expressed on LYMPHOID CELLS and MYELOID CELLS.

Descriptor ID	D051997
MeSH Number(s)	D08.811.277.450.430.400.060.500 D12.776.543.550.045
Concept/Terms	ADP-ribosyl Cyclase 1 ADP-ribosyl Cyclase 1 1, ADP-ribosyl Cyclase ADP ribosyl Cyclase 1 Cyclase 1, ADP-ribosyl T10 Antigen Antigen, T10 NIM-R5 Antigen NIM R5 Antigen CD38 Antigens ADPR Cyclase T10 Cyclase T10, ADPR Acute Lymphoblastic Leukemia Cells Antigen CD38 Lymphocyte Differentiation Antigen CD38 Antigens, CD38 CD38 Antigen ADPR Cyclase CD38 CD38, ADPR Cyclase Cyclase CD38, ADPR

Below are MeSH descriptors whose meaning is more general than "ADP-ribosyl Cyclase 1".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Glycoside Hydrolases [D08.811.277.450]
N-Glycosyl Hydrolases [D08.811.277.450.430]
NAD+ Nucleosidase [D08.811.277.450.430.400]
ADP-ribosyl Cyclase [D08.811.277.450.430.400.060]
ADP-ribosyl Cyclase 1 [D08.811.277.450.430.400.060.500]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Membrane Glycoproteins [D12.776.543.550]
ADP-ribosyl Cyclase 1 [D12.776.543.550.045]

Below are MeSH descriptors whose meaning is related to "ADP-ribosyl Cyclase 1".

Below are MeSH descriptors whose meaning is more specific than "ADP-ribosyl Cyclase 1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "ADP-ribosyl Cyclase 1" by people in this website by year, and whether "ADP-ribosyl Cyclase 1" was a major or minor topic of these publications.

Bar chart showing 11 publications over 8 distinct years, with a maximum of 2 publications in 2003 and 2017 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
2001	0	1	1
2002	0	1	1
2003	0	2	2
2016	1	0	1
2017	1	1	2
2019	2	0	2
2020	1	0	1

Below are the most recent publications written about "ADP-ribosyl Cyclase 1" by people in Profiles.

Kar A, Mehrotra S, Chatterjee S. CD38: T Cell Immuno-Metabolic Modulator. Cells. 2020 07 17; 9(7).

View in: PubMed
Chatterjee S, Chakraborty P, Mehrotra S. CD38-NAD+-Sirt1 axis in T cell immunotherapy. Aging (Albany NY). 2019 10 23; 11(20):8743-8744.

View in: PubMed
Gandhi UH, Cornell RF, Lakshman A, Gahvari ZJ, McGehee E, Jagosky MH, Gupta R, Varnado W, Fiala MA, Chhabra S, Malek E, Mansour J, Paul B, Barnstead A, Kodali S, Neppalli A, Liedtke M, Narayana S, Godby KN, Kang Y, Kansagra A, Umyarova E, Scott EC, Hari P, Vij R, Usmani SZ, Callander NS, Kumar SK, Costa LJ. Outcomes of patients with multiple myeloma refractory to CD38-targeted monoclonal antibody therapy. Leukemia. 2019 09; 33(9):2266-2275.

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Chatterjee S, Daenthanasanmak A, Chakraborty P, Wyatt MW, Dhar P, Selvam SP, Fu J, Zhang J, Nguyen H, Kang I, Toth K, Al-Homrani M, Husain M, Beeson G, Ball L, Helke K, Husain S, Garrett-Mayer E, Hardiman G, Mehrotra M, Nishimura MI, Beeson CC, Bupp MG, Wu J, Ogretmen B, Paulos CM, Rathmell J, Yu XZ, Mehrotra S. CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response. Cell Metab. 2018 01 09; 27(1):85-100.e8.

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Luo Z, Li Z, Martin L, Hu Z, Wu H, Wan Z, Kilby M, Heath SL, Huang L, Jiang W. Increased Natural Killer Cell Activation in HIV-Infected Immunologic Non-Responders Correlates with CD4+ T Cell Recovery after Antiretroviral Therapy and Viral Suppression. PLoS One. 2017; 12(1):e0167640.

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Würsch D, Ormsby CE, Romero-Rodríguez DP, Olvera-García G, Zúñiga J, Jiang W, Pérez-Patrigeon S, Espinosa E. CD38 Expression in a Subset of Memory T Cells Is Independent of Cell Cycling as a Correlate of HIV Disease Progression. Dis Markers. 2016; 2016:9510756.

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Ishikawa F, Livingston AG, Minamiguchi H, Wingard JR, Ogawa M. Human cord blood long-term engrafting cells are CD34+ CD38-. Leukemia. 2003 May; 17(5):960-4.

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Higuchi Y, Zeng H, Ogawa M. CD38 expression by hematopoietic stem cells of newborn and juvenile mice. Leukemia. 2003 Jan; 17(1):171-4.

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Ogawa M. Changing phenotypes of hematopoietic stem cells. Exp Hematol. 2002 Jan; 30(1):3-6.

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Tajima F, Deguchi T, Laver JH, Zeng H, Ogawa M. Reciprocal expression of CD38 and CD34 by adult murine hematopoietic stem cells. Blood. 2001 May 01; 97(9):2618-24.

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