"gamma-Glutamyl Hydrolase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Catalyzes the hydrolysis of pteroylpolyglutamic acids in gamma linkage to pterolylmonoglutamic acid and free glutamic acid. EC 3.4.19.9.
| Descriptor ID |
D011623
|
| MeSH Number(s) |
D08.811.277.656.350.245.280
|
| Concept/Terms |
gamma-Glutamyl Hydrolase- gamma-Glutamyl Hydrolase
- gamma Glutamyl Hydrolase
- Folylpolyglutamate Hydrolase
- Pteroyl Polyglutamate Hydrolase
- Carboxypeptidase G
- Folyl Poly-gamma-Glutamate Carboxypeptidase
- Folacin Conjugase
- Folate Conjugase
- Folate Hydrolyzing Enzyme
- Folyl Conjugate Synthetase
- Folyl Polyglutamate Cleavage Enzyme
- Conjugase
|
Below are MeSH descriptors whose meaning is more general than "gamma-Glutamyl Hydrolase".
Below are MeSH descriptors whose meaning is more specific than "gamma-Glutamyl Hydrolase".
This graph shows the total number of publications written about "gamma-Glutamyl Hydrolase" by people in this website by year, and whether "gamma-Glutamyl Hydrolase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "gamma-Glutamyl Hydrolase" by people in Profiles.
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Genes involved with folate uptake and distribution and their association with colorectal cancer risk. Cancer Causes Control. 2010 Apr; 21(4):597-608.
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Multifactorial resistance to 5,10-dideazatetrahydrofolic acid in cell lines derived from human lymphoblastic leukemia CCRF-CEM. Cancer Res. 1995 Feb 01; 55(3):566-73.
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The role of folylpolyglutamate synthetase and gamma-glutamyl hydrolase in altering cellular folyl- and antifolylpolyglutamates. Adv Enzyme Regul. 1987; 26:147-55.
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Hydrolytic cleavage of methotrexate gamma-polyglutamates by folylpolyglutamyl hydrolase derived from various tumors and normal tissues of the mouse. Cancer Res. 1986 May; 46(5):2230-5.
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Effects of growth rate and methotrexate on folate polyglutamates and folylpolyglutamate hydrolase activity in Krebs ascites cells. Biochem Cell Biol. 1986 Apr; 64(4):363-7.
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Comparison of folylpolyglutamate hydrolases of mouse liver, kidney, muscle and brain. Mol Cell Biochem. 1982 Mar 19; 43(2):81-7.