Chemical and Drug Induced Liver Injury

"Chemical and Drug Induced Liver Injury" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.

Descriptor ID	D056486
MeSH Number(s)	C06.552.195 C25.100.562 C25.723.260
Concept/Terms	Chemical and Drug Induced Liver Injury Chemical and Drug Induced Liver Injury Chemically-Induced Liver Toxicity Chemically-Induced Liver Toxicity Chemically Induced Liver Toxicity Chemically-Induced Liver Toxicities Liver Toxicities, Chemically-Induced Liver Toxicity, Chemically-Induced Toxicities, Chemically-Induced Liver Toxicity, Chemically-Induced Liver Drug-Induced Acute Liver Injury Drug-Induced Acute Liver Injury Drug Induced Acute Liver Injury Liver Injury, Drug-Induced, Acute Acute Liver Injury, Drug-Induced Acute Liver Injury, Drug Induced Hepatitis, Toxic Hepatitis, Toxic Toxic Hepatitis Hepatitides, Toxic Toxic Hepatitides Drug-Induced Liver Disease Drug-Induced Liver Disease Disease, Drug-Induced Liver Diseases, Drug-Induced Liver Drug Induced Liver Disease Drug-Induced Liver Diseases Liver Disease, Drug-Induced Liver Diseases, Drug-Induced Drug-Induced Liver Injury Drug Induced Liver Injury Drug-Induced Liver Injuries Injuries, Drug-Induced Liver Injury, Drug-Induced Liver Liver Injuries, Drug-Induced Liver Injury, Drug-Induced Liver Injury, Drug Induced Hepatitis, Drug-Induced Hepatitis, Drug-Induced Drug-Induced Hepatitides Drug-Induced Hepatitis Hepatitides, Drug-Induced Hepatitis, Drug Induced

Below are MeSH descriptors whose meaning is more general than "Chemical and Drug Induced Liver Injury".

Diseases [C]
Digestive System Diseases [C06]
Liver Diseases [C06.552]
Chemical and Drug Induced Liver Injury [C06.552.195]
Chemically-Induced Disorders [C25]
Drug-Related Side Effects and Adverse Reactions [C25.100]
Chemical and Drug Induced Liver Injury [C25.100.562]
Poisoning [C25.723]
Chemical and Drug Induced Liver Injury [C25.723.260]

Below are MeSH descriptors whose meaning is related to "Chemical and Drug Induced Liver Injury".

Below are MeSH descriptors whose meaning is more specific than "Chemical and Drug Induced Liver Injury".

Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury, Chronic

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Chemical and Drug Induced Liver Injury" by people in this website by year, and whether "Chemical and Drug Induced Liver Injury" was a major or minor topic of these publications.

Bar chart showing 73 publications over 22 distinct years, with a maximum of 8 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	2	2
1996	2	0	2
1997	0	1	1
2002	2	1	3
2004	1	0	1
2005	1	0	1
2006	1	0	1
2007	2	1	3
2008	1	0	1
2009	1	0	1
2010	4	0	4
2011	1	1	2
2012	3	2	5
2013	5	0	5
2014	8	0	8
2015	2	1	3
2016	2	0	2
2017	3	1	4
2019	5	1	6
2020	7	0	7
2021	7	0	7
2022	4	0	4

Below are the most recent publications written about "Chemical and Drug Induced Liver Injury" by people in Profiles.

Samuvel DJ, Nguyen NT, Jaeschke H, Lemasters JJ, Wang X, Choo YM, Hamann MT, Zhong Z. Platanosides, a Potential Botanical Drug Combination, Decrease Liver Injury Caused by Acetaminophen Overdose in Mice. J Nat Prod. 2022 07 22; 85(7):1779-1788.

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Adelusi OB, Ramachandran A, Lemasters JJ, Jaeschke H. The role of Iron in lipid peroxidation and protein nitration during acetaminophen-induced liver injury in mice. Toxicol Appl Pharmacol. 2022 06 15; 445:116043.

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Hermann RP, Rockey DC, Suzuki A, Merz M, Tillmann HL. A novel phenotype-based drug-induced liver injury causality assessment tool (DILI-CAT) allows for signal confirmation in early drug development. Aliment Pharmacol Ther. 2022 04; 55(8):1028-1037.

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Ahmad J, Barnhart HX, Bonacini M, Ghabril M, Hayashi PH, Odin JA, Rockey DC, Rossi S, Serrano J, Tillmann HL, Kleiner DE. Value of liver biopsy in the diagnosis of drug-induced liver injury. J Hepatol. 2022 05; 76(5):1070-1078.

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Vuppalanchi R, Bonkovsky HL, Ahmad J, Barnhart H, Durazo F, Fontana RJ, Gu J, Khan I, Kleiner DE, Koh C, Rockey DC, Phillips EJ, Li YJ, Serrano J, Stolz A, Tillmann HL, Seeff LB, Hoofnagle JH, Navarro VJ. Garcinia cambogia, Either Alone or in Combination With Green Tea, Causes Moderate to Severe Liver Injury. Clin Gastroenterol Hepatol. 2022 06; 20(6):e1416-e1425.

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Stravitz RT, Fontana RJ, Meinzer C, Durkalski-Mauldin V, Hanje AJ, Olson J, Koch D, Hamid B, Schilsky ML, McGuire B, Ganger D, Liou I, Karvellas CJ, Rule JA, Lisman T, Clasen K, Reuben A, Cripps M, Lee WM. Coagulopathy, Bleeding Events, and Outcome According to Rotational Thromboelastometry in Patients With Acute Liver Injury/Failure. Hepatology. 2021 08; 74(2):937-949.

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Fontana RJ, Stravitz RT, Durkalski V, Hanje J, Hameed B, Koch D, Reuben A, Ganger D, Olson J, Liou I, McGuire BM, Clasen K, Lee WM. Prognostic Value of the 13 C-Methacetin Breath Test in Adults with Acute Liver Failure and Non-acetaminophen Acute Liver Injury. Hepatology. 2021 08; 74(2):961-972.

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Elston D. This Month in JAAD: June 2021. J Am Acad Dermatol. 2021 06; 84(6):1542.

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Hoofnagle JH, Bonkovsky HL, Phillips EJ, Li YJ, Ahmad J, Barnhart H, Durazo F, Fontana RJ, Gu J, Khan I, Kleiner DE, Koh C, Rockey DC, Seeff LB, Serrano J, Stolz A, Tillmann HL, Vuppalanchi R, Navarro VJ. HLA-B*35:01 and Green Tea-Induced Liver Injury. Hepatology. 2021 06; 73(6):2484-2493.

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Baum RA, Woolum JA, Bailey AM, Howell MM, Weant KA, Geraghty L, Mohan S, Webb AN, Su MK, Akpunonu P. Evaluation of Dosing Strategies of N-acetylcysteine for Acetaminophen Toxicity in Patients Greater than 100 Kilograms: Should the Dosage Cap Be Used? J Med Toxicol. 2021 07; 17(3):241-249.

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