"Replication Protein A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A single-stranded DNA-binding protein that is found in EUKARYOTIC CELLS. It is required for DNA REPLICATION; DNA REPAIR; and GENETIC RECOMBINATION.
| Descriptor ID |
D051716
|
| MeSH Number(s) |
D12.776.260.700
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| Concept/Terms |
Replication Protein A- Replication Protein A
- Single-Strand Binding Protein RP-A
- Single Strand Binding Protein RP A
- Replication Factor A Single-Stranded DNA-Binding Protein
- Replication Factor A Single Stranded DNA Binding Protein
- Replication Factor A
- DNA Replication Factor A
|
Below are MeSH descriptors whose meaning is more general than "Replication Protein A".
Below are MeSH descriptors whose meaning is more specific than "Replication Protein A".
This graph shows the total number of publications written about "Replication Protein A" by people in this website by year, and whether "Replication Protein A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2007 | 2 | 0 | 2 |
| 2008 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
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Below are the most recent publications written about "Replication Protein A" by people in Profiles.
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Expression and regulation of RAD51 mediate cellular responses to chemotherapeutics. Biochem Pharmacol. 2012 Mar 15; 83(6):741-6.
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Mechanism of RAD51-dependent DNA interstrand cross-link repair. Science. 2011 Jul 01; 333(6038):84-7.
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DNA damage and homologous recombination signaling induced by thymidylate deprivation. Biochem Pharmacol. 2008 Oct 15; 76(8):987-96.
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Cell cycle-and proteasome-dependent formation of etoposide-induced replication protein A (RPA) or Mre11/Rad50/Nbs1 (MRN) complex repair foci. Cell Cycle. 2007 Oct 01; 6(19):2399-407.
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Replication protein A is required for etoposide-induced assembly of MRE11/RAD50/NBS1 complex repair foci. Cell Cycle. 2007 Oct 01; 6(19):2408-16.
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DNA damage induced hyperphosphorylation of replication protein A. 1. Identification of novel sites of phosphorylation in response to DNA damage. Biochemistry. 2005 Jun 14; 44(23):8428-37.
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DNA lesion-specific co-localization of the Mre11/Rad50/Nbs1 (MRN) complex and replication protein A (RPA) to repair foci. J Biol Chem. 2005 Apr 01; 280(13):12927-34.
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Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks. J Biol Chem. 2004 Aug 13; 279(33):34802-10.
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The contrahelicase activities of the replication terminator proteins of Escherichia coli and Bacillus subtilis are helicase-specific and impede both helicase translocation and authentic DNA unwinding. J Biol Chem. 1995 Dec 08; 270(49):29138-44.