"Calcium Channel Agonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that increase calcium influx into calcium channels of excitable tissues. This causes vasoconstriction in VASCULAR SMOOTH MUSCLE and/or CARDIAC MUSCLE cells as well as stimulation of insulin release from pancreatic islets. Therefore, tissue-selective calcium agonists have the potential to combat cardiac failure and endocrinological disorders. They have been used primarily in experimental studies in cell and tissue culture.
| Descriptor ID |
D002120
|
| MeSH Number(s) |
D27.505.519.562.124 D27.505.954.411.793.205
|
| Concept/Terms |
Calcium Channel Agonists- Calcium Channel Agonists
- Agonists, Calcium Channel
- Channel Agonists, Calcium
- Calcium Channel Activators
- Activators, Calcium Channel
- Channel Activators, Calcium
- Calcium Channel Agonist
- Agonist, Calcium Channel
- Channel Agonist, Calcium
|
Below are MeSH descriptors whose meaning is more general than "Calcium Channel Agonists".
Below are MeSH descriptors whose meaning is more specific than "Calcium Channel Agonists".
This graph shows the total number of publications written about "Calcium Channel Agonists" by people in this website by year, and whether "Calcium Channel Agonists" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Calcium Channel Agonists" by people in Profiles.
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Rubinstein J, Woo JG, Garcia AM, Alsaied T, Li J, Lunde PK, Moore RA, Laasmaa M, Sammons A, Mays WA, Miyamoto SD, Louch WE, Veldtman GR. Probenecid Improves Cardiac Function in Subjects with a Fontan Circulation and Augments Cardiomyocyte Calcium Homeostasis. Pediatr Cardiol. 2020 Dec; 41(8):1675-1688.
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Chirasani VR, Xu L, Addis HG, Pasek DA, Dokholyan NV, Meissner G, Yamaguchi N. A central core disease mutation in the Ca2+-binding site of skeletal muscle ryanodine receptor impairs single-channel regulation. Am J Physiol Cell Physiol. 2019 08 01; 317(2):C358-C365.
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Findlay VJ, Moretz RE, Wang C, Vaena SG, Bandurraga SG, Ashenafi M, Marshall DT, Watson DK, Camp ER. Slug expression inhibits calcitriol-mediated sensitivity to radiation in colorectal cancer. Mol Carcinog. 2014 Feb; 53 Suppl 1:E130-9.
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Zhang ZR, Chu WF, Song B, Gooz M, Zhang JN, Yu CJ, Jiang S, Baldys A, Gooz P, Steele S, Owsianik G, Nilius B, Komlosi P, Bell PD. TRPP2 and TRPV4 form an EGF-activated calcium permeable channel at the apical membrane of renal collecting duct cells. PLoS One. 2013; 8(8):e73424.
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Movafagh S, Cleemann L, Morad M. Regulation of cardiac Ca(2+) channel by extracellular Na(+). Cell Calcium. 2011 Mar; 49(3):162-73.
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Mulholland PJ, Becker HC, Woodward JJ, Chandler LJ. Small conductance calcium-activated potassium type 2 channels regulate alcohol-associated plasticity of glutamatergic synapses. Biol Psychiatry. 2011 Apr 01; 69(7):625-32.
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Sribnick EA, Del Re AM, Ray SK, Woodward JJ, Banik NL. Estrogen attenuates glutamate-induced cell death by inhibiting Ca2+ influx through L-type voltage-gated Ca2+ channels. Brain Res. 2009 Jun 18; 1276:159-70.
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Potter DE, Ogidigben MJ, Chu TC. Lisuride acts at multiple sites to induce ocular hypotension and mydriasis. Pharmacology. 1998 Nov; 57(5):249-60.
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Houck WV, Thomas CV, Doscher MA, Wang YH, Hebbar L, Joshi JD, Mukherjee R, Crawford FA, Spinale FG. Downstream defects in beta-adrenergic signaling and relation to myocyte contractility after cardioplegic arrest. J Thorac Cardiovasc Surg. 1998 Jan; 115(1):190-9.
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Mayeux PR, Mais DE, Halushka PV. Interactions of dihydropyridine Ca2+ channel agonists with the human platelet thromboxane A2/prostaglandin H2 receptor. Eur J Pharmacol. 1991 Jan 25; 206(1):15-21.