"Ionophores" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Chemical agents that increase the permeability of biological or artificial lipid membranes to specific ions. Most ionophores are relatively small organic molecules that act as mobile carriers within membranes or coalesce to form ion permeable channels across membranes. Many are antibiotics, and many act as uncoupling agents by short-circuiting the proton gradient across mitochondrial membranes.
Descriptor ID |
D007476
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MeSH Number(s) |
D27.505.519.562.374 D27.720.395
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ionophores".
Below are MeSH descriptors whose meaning is more specific than "Ionophores".
This graph shows the total number of publications written about "Ionophores" by people in this website by year, and whether "Ionophores" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
1999 | 2 | 1 | 3 |
2000 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2003 | 1 | 2 | 3 |
2004 | 1 | 1 | 2 |
2005 | 0 | 3 | 3 |
2006 | 0 | 2 | 2 |
2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ionophores" by people in Profiles.
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Salinomycin targets the genome of radioresistant cells in glioblastomas. Neuro Oncol. 2020 02 20; 22(2):167-168.
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Calpeptin provides functional neuroprotection to rat retinal ganglion cells following Ca2+ influx. Brain Res. 2006 Apr 21; 1084(1):146-57.
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Glutamate stimulates oligodendrocyte progenitor migration mediated via an alphav integrin/myelin proteolipid protein complex. J Neurosci. 2006 Mar 01; 26(9):2458-66.
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Role of pH in protection by low sodium against hypoxic injury in isolated perfused rat livers. J Hepatol. 2006 May; 44(5):894-901.
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Calpain activation in apoptosis of ventral spinal cord 4.1 (VSC4.1) motoneurons exposed to glutamate: calpain inhibition provides functional neuroprotection. J Neurosci Res. 2005 Aug 15; 81(4):551-62.
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Primaquine-induced hemolytic anemia: role of membrane lipid peroxidation and cytoskeletal protein alterations in the hemotoxicity of 5-hydroxyprimaquine. J Pharmacol Exp Ther. 2005 Aug; 314(2):838-45.
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Bryostatin-1 in combination with calcium ionophore promotes the maturation of human umbilical cord-blood monocyte-derived dendritic cells capable of activating neonatal alloreactive T cells. Cell Immunol. 2004 Sep-Oct; 231(1-2):8-13.
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Calcium-induced calpain mediates apoptosis via caspase-3 in a mouse photoreceptor cell line. J Biol Chem. 2004 Aug 20; 279(34):35564-72.
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Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release. J Biol Chem. 2003 Oct 03; 278(40):38206-13.
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Estrogen attenuates oxidative stress-induced apoptosis in C6 glial cells. Brain Res. 2003 May 09; 971(2):178-88.