"Fibrinogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
| Descriptor ID |
D005340
|
| MeSH Number(s) |
D12.776.124.050.250 D12.776.124.125.500 D12.776.811.300 D23.119.490
|
| Concept/Terms |
Fibrinogen- Fibrinogen
- Blood Coagulation Factor I
- Coagulation Factor I
- Factor I, Coagulation
- Factor I
|
Below are MeSH descriptors whose meaning is more general than "Fibrinogen".
Below are MeSH descriptors whose meaning is more specific than "Fibrinogen".
This graph shows the total number of publications written about "Fibrinogen" by people in this website by year, and whether "Fibrinogen" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 3 | 3 | 6 |
| 2006 | 0 | 2 | 2 |
| 2007 | 2 | 0 | 2 |
| 2008 | 1 | 1 | 2 |
| 2009 | 3 | 0 | 3 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 2 | 2 |
| 2019 | 0 | 2 | 2 |
| 2020 | 0 | 2 | 2 |
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Below are the most recent publications written about "Fibrinogen" by people in Profiles.
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Clair DG. Managing the coagulation system in patients with arterial disease. J Vasc Surg. 2021 03; 73(3):940-941.
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Groves DS, Welsby IJ, Naik BI, Tanaka K, Hauck JN, Greenberg CS, Winegar DA, Viola F. Multicenter Evaluation of the Quantra QPlus System in Adult Patients Undergoing Major Surgical Procedures. Anesth Analg. 2020 04; 130(4):899-909.
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Brash JL, Horbett TA, Latour RA, Tengvall P. The blood compatibility challenge. Part 2: Protein adsorption phenomena governing blood reactivity. Acta Biomater. 2019 08; 94:11-24.
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O'Leary JG, Greenberg CS, Patton HM, Caldwell SH. AGA Clinical Practice Update: Coagulation in Cirrhosis. Gastroenterology. 2019 07; 157(1):34-43.e1.
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Baker NL, Hunt KJ, Stevens DR, Jarai G, Rosen GD, Klein RL, Virella G, Lopes-Virella MF. Association Between Inflammatory Markers and Progression to Kidney Dysfunction: Examining Different Assessment Windows in Patients With Type 1 Diabetes. Diabetes Care. 2018 01; 41(1):128-135.
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Lee SJ, Hong JM, Lee SE, Kang DR, Ovbiagele B, Demchuk AM, Lee JS. Association of fibrinogen level with early neurological deterioration among acute ischemic stroke patients with diabetes. BMC Neurol. 2017 May 19; 17(1):101.
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Wang J, Sun Z, Gou W, Adams DB, Cui W, Morgan KA, Strange C, Wang H. a-1 Antitrypsin Enhances Islet Engraftment by Suppression of Instant Blood-Mediated Inflammatory Reaction. Diabetes. 2017 04; 66(4):970-980.
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Chung YC, Kruyer A, Yao Y, Feierman E, Richards A, Strickland S, Norris EH. Hyperhomocysteinemia exacerbates Alzheimer's disease pathology by way of the ß-amyloid fibrinogen interaction. J Thromb Haemost. 2016 07; 14(7):1442-52.
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Hanna JM, Keenan JE, Wang H, Andersen ND, Gaca JG, Lombard FW, Welsby IJ, Hughes GC. Use of human fibrinogen concentrate during proximal aortic reconstruction with deep hypothermic circulatory arrest. J Thorac Cardiovasc Surg. 2016 Feb; 151(2):376-82.
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Lai TS, Greenberg CS. Histaminylation of fibrinogen by tissue transglutaminase-2 (TGM-2): potential role in modulating inflammation. Amino Acids. 2013 Oct; 45(4):857-64.