"Sulfamethoxazole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
| Descriptor ID |
D013420
|
| MeSH Number(s) |
D02.065.884.725.867 D02.092.146.807.867 D02.886.590.700.725.867
|
| Concept/Terms |
Sulfamethoxazole- Sulfamethoxazole
- Sulphamethoxazole
- Sulfamethylisoxazole
- Sulfisomezole
|
Below are MeSH descriptors whose meaning is more general than "Sulfamethoxazole".
Below are MeSH descriptors whose meaning is more specific than "Sulfamethoxazole".
This graph shows the total number of publications written about "Sulfamethoxazole" by people in this website by year, and whether "Sulfamethoxazole" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 1999 | 2 | 0 | 2 |
| 2000 | 0 | 1 | 1 |
| 2005 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sulfamethoxazole" by people in Profiles.
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Wei CH, Sanchez-Huerta C, Leiknes T, Amy G, Zhou H, Hu X, Fang Q, Rong H. Removal and biotransformation pathway of antibiotic sulfamethoxazole from municipal wastewater treatment by anaerobic membrane bioreactor. J Hazard Mater. 2019 12 15; 380:120894.
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Moran RA, Hall RM. pBuzz: A cryptic rolling-circle plasmid from a commensal Escherichia coli has two inversely oriented oriTs and is mobilised by a B/O plasmid. Plasmid. 2019 01; 101:10-19.
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Khan FD, Roychowdhury S, Nemes R, Vyas PM, Woster PM, Svensson CK. Effect of pro-inflammatory cytokines on the toxicity of the arylhydroxylamine metabolites of sulphamethoxazole and dapsone in normal human keratinocytes. Toxicology. 2006 Feb 01; 218(2-3):90-9.
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Vyas PM, Roychowdhury S, Woster PM, Svensson CK. Reactive oxygen species generation and its role in the differential cytotoxicity of the arylhydroxylamine metabolites of sulfamethoxazole and dapsone in normal human epidermal keratinocytes. Biochem Pharmacol. 2005 Jul 15; 70(2):275-86.
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Reilly TP, Lash LH, Doll MA, Hein DW, Woster PM, Svensson CK. A role for bioactivation and covalent binding within epidermal keratinocytes in sulfonamide-induced cutaneous drug reactions. J Invest Dermatol. 2000 Jun; 114(6):1164-73.
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Reilly TP, MacArthur RD, Farrough MJ, Crane LR, Woster PM, Svensson CK. Is hydroxylamine-induced cytotoxicity a valid marker for hypersensitivity reactions to sulfamethoxazole in human immunodeficiency virus-infected individuals? J Pharmacol Exp Ther. 1999 Dec; 291(3):1356-64.
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Reilly TP, Woster PM, Svensson CK. Methemoglobin formation by hydroxylamine metabolites of sulfamethoxazole and dapsone: implications for differences in adverse drug reactions. J Pharmacol Exp Ther. 1999 Mar; 288(3):951-9.
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Reilly TP, Bellevue FH, Woster PM, Svensson CK. Comparison of the in vitro cytotoxicity of hydroxylamine metabolites of sulfamethoxazole and dapsone. Biochem Pharmacol. 1998 Mar 15; 55(6):803-10.
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Soper DE, Merrill-Nach S. Successful therapy of penicillinase-producing Neisseria gonorrhoeae pharyngeal infection during pregnancy. Obstet Gynecol. 1986 Aug; 68(2):290-1.
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Gaskins JD, Holt RJ, Kyong CU, Weart CW, Ward J. Chemoprophylaxis of recurrent otitis media using trimethoprim/sulfamethoxazole. Drug Intell Clin Pharm. 1982 May; 16(5):387-90.