Iron Regulatory Protein 2
"Iron Regulatory Protein 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron regulatory elements found on mRNAs involved in iron metabolism and regulates their translation. Its rate of degradation is increased in the presence of IRON.
Descriptor ID |
D035942
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MeSH Number(s) |
D08.811.520.241.300.050.750 D12.776.157.427.374.375.961 D12.776.157.725.437 D12.776.494.750 D12.776.556.579.374.375.962 D12.776.664.962.437
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Concept/Terms |
Iron Regulatory Protein 2- Iron Regulatory Protein 2
- IRP-2 RNA-binding protein
- IRP 2 RNA binding protein
- RNA-binding protein, IRP-2
- IREB2 Protein
- IRP2 Protein
- Iron-Responsive-Element Binding Protein 2
- IRE-BP2
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Below are MeSH descriptors whose meaning is more general than "Iron Regulatory Protein 2".
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This graph shows the total number of publications written about "Iron Regulatory Protein 2" by people in this website by year, and whether "Iron Regulatory Protein 2" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "Iron Regulatory Protein 2" by people in Profiles.
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Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene. Am J Hum Genet. 2009 Oct; 85(4):493-502.